POU5F2 - POU domain class 5, transcription factor 2 Gene

Also Known as SPRM-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 134187

About POU5F2

This gene has 1 transcript (splice variant), 511 orthologues and 17 paralogues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

POU5F2 Products (1)

mRNA Protein Name
NM_153216.2 NP_694948.1 POU domain, class 5, transcription factor 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

POU5F2 Protein Structure

Pou

Pou: Pou domain - N-terminal to homeobox domain (123 - 192)

Homeobox

Homeobox: Homeobox domain (223 - 261)

  • 0
  • 100
  • 200
  • 300
  • 328 a.a.
Protein Preferred Names Protein Names

POU domain, class 5, transcription factor 2

  • sperm 1 POU domain transcription factor

POU5F2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
POU5F2 Q8N7G0 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra
POU5F2 Q8N7G0 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Bosch-Boonstra-Schaaf Optic Atrophy Syndrome

  • BBSOAS

  • Optic Atrophy-Intellectual Disability Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS10911 POU5F2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus POU5F2 MGD MGI:1922757
Rattus norvegicus POU5F2 RGD RGD:1589456