1. Gene
  2. POU5F2 - POU domain class 5, transcription factor 2 Gene

POU5F2 - POU domain class 5, transcription factor 2 Gene

Homo sapiens

Also known as SPRM-1

Gene ID: 134187 | Gene type: protein coding

About POU5F2

This gene has 1 transcript (splice variant), 511 orthologues and 17 paralogues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

POU5F2 Products(1)

mRNA Protein Name
NM_153216.2 NP_694948.1 POU domain, class 5, transcription factor 2

POU5F2 Protein Structure

Pou

Pou: Pou domain - N-terminal to homeobox domain (123 - 192)

Homeobox

Homeobox: Homeobox domain (223 - 261)

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  • 328 a.a.
Protein Preferred Names Protein Names

POU domain, class 5, transcription factor 2

sperm 1 POU domain transcription factor

Related Diseases

Diseases Alias
Bosch-Boonstra-Schaaf Optic Atrophy Syndrome

BBSOAS

Optic Atrophy-Intellectual Disability Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus POU5F2 MGD MGI:1922757
Rattus norvegicus POU5F2 RGD RGD:1589456