DPY19L3 - dpy-19 like C-mannosyltransferase 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 147991

About DPY19L3

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:32,405,770-32,485,890 (from NCBI)

This gene has 12 transcripts (splice variants), 203 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 5.7), prostate (RPKM 5.6) and 25 other tissues.

Summary

Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. [provided by Alliance of Genome Resources, Apr 2022]

DPY19L3 Products (2)

mRNA Protein Name
NM_001172774.2 NP_001166245.1 probable C-mannosyltransferase DPY19L3
NM_207325.3 NP_997208.2 probable C-mannosyltransferase DPY19L3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables mannosyltransferase activity IDA
IDA: Inferred from direct assay
29405629 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
29405629 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DPY19L3 Protein Structure

Dpy19

Dpy19: Q-cell neuroblast polarisation (54 - 712)

  • 0
  • 200
  • 400
  • 600
  • 716 a.a.
Protein Preferred Names Protein Names

probable C-mannosyltransferase DPY19L3

  • dpy-19 like 3

Related Diseases

Diseases Alias
Spermatogenic Failure 9

  • Male Infertility Due To Globozoospermia

  • SPGF9

  • Male Infertility Due To Round-Headed Spermatozoa

  • Globozoospermia, Complete

  • Globozoospermia, Total

  • Globozoospermia

  • Globozoospermia Syndrome

  • Round-Headed Sperm Syndrome

  • Globozoospermia Complete

  • Globozoospermia Total
Podoconiosis

  • PDCOS

  • Podoconiosis, Susceptibility To

  • Nonfilarial Elephantiasis Of Lower Legs

  • Nonfilarial Elephantiasis Of Lower Legs, Susceptibility To

  • Endemic Nonfilarial Elephantiasis

  • Endemic Nonfilarial Elephantiasis, Susceptibility To

  • Lymphostatic Verrucosis

  • Lymphostatic Verrucosis, Susceptibility To

  • Elephantiasis

  • Endemic Non-Filarial Elephantiasis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS03977 DPY19L3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DPY19L3 MGD MGI:2443952
Felis catus DPY19L3 VGNC VGNC:61612
Rattus norvegicus DPY19L3 RGD RGD:1308334
Canis familiaris DPY19L3 VGNC VGNC:49600
Macaca mulatta DPY19L3 VGNC VGNC:71912
Bos taurus DPY19L3 VGNC VGNC:49144
Others DPY19L3 NCBI