Alyref - Aly/REF export factor Gene

Also Known as Aly; Ref1; Tho4; Thoc4; Ref1-I; Refbp1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21681

Summary

Enables RNA binding activity and single-stranded DNA binding activity. Predicted to be involved in several processes, including mRNA export from nucleus; regulation of nucleobase-containing compound metabolic process; and viral mRNA export from host cell nucleus. Predicted to act upstream of or within RNA splicing; mRNA processing; and mRNA transport. Predicted to be located in cytoplasm. Predicted to be part of catalytic step 2 spliceosome; exon-exon junction complex; and transcription export complex. Predicted to be active in nucleus. Predicted to colocalize with chromosome, telomeric region. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human ALYREF (Aly/REF export factor). [provided by Alliance of Genome Resources, Apr 2022]

Alyref Products (1)

mRNA Protein Name
NM_011568.1 NP_035698.1 THO complex subunit 4
Protein Preferred Names Protein Names

THO complex subunit 4

  • RNA and export factor binding protein 1

  • THO complex 4

  • Tcra enhancer-binding factor interacting protein 1

  • ally of AML-1 and LEF-1

  • transcriptional coactivator Aly/REF

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00639 ALYREF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19247 Alyref Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25736 Alyref Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Alyref NCBI NCBI:10189