Hlf - hepatic leukemia factor Gene

Also Known as E230015K02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217082

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within skeletal muscle cell differentiation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human HLF (HLF transcription factor, PAR bZIP family member). [provided by Alliance of Genome Resources, Apr 2022]

Hlf Products (9)

mRNA Protein Name
NM_001403985.1 NP_001390914.1 hepatic leukemia factor isoform 2
NM_001403986.1 NP_001390915.1 hepatic leukemia factor isoform 3
NM_001403988.1 NP_001390917.1 hepatic leukemia factor isoform 4
NM_001403989.1 NP_001390918.1 hepatic leukemia factor isoform 4
NM_001403991.1 NP_001390920.1 hepatic leukemia factor isoform 4
NM_001403993.1 NP_001390922.1 hepatic leukemia factor isoform 5
NM_001403995.1 NP_001390924.1 hepatic leukemia factor isoform 5
NM_001403997.1 NP_001390926.1 hepatic leukemia factor isoform 5
NM_172563.4 NP_766151.1 hepatic leukemia factor isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
22147266 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatic leukemia factor

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname Wirkung
Reinheit Phase
HY-106228 HLF1-11 Inhibitor 99.73% Phase 2

Pre-clinical Phase

Bioactive Molecules (11)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04409 EPAS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-144075 JAK-IN-19 Inhibitor / Unkown
HY-146724 Dot1L-IN-7 Inhibitor / Unkown
HY-147946 PDE1-IN-4 Inhibitor / Unkown
HY-P11131 hLF (28-34) Inhibitor / Unkown
HY-RS06219 HLF Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-172462 Mtb-IN-11 Inhibitor / Unkown
HY-RS18116 Hlf Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18998 Epas1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24590 Hlf Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25487 Epas1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P990867 Anti-CD220/Insulin Receptor Antibody (IR 83-22) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hlf NCBI NCBI:3131