1. Epigenetics
  2. Histone Methyltransferase
  3. Dot1L-IN-7

Dot1L-IN-7 

Cat. No.: HY-146724
Handling Instructions

Dot1L-IN-7 (compound 25) is a potent and selective disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 of 1.0 μM. Dot1L-IN-7 selectively killed Mixed Lineage Leukemia (MLL)-AF9 without showing any effect on the growth of E2A-HLF cells.

For research use only. We do not sell to patients.

Dot1L-IN-7 Chemical Structure

Dot1L-IN-7 Chemical Structure

CAS No. : 2580940-76-5

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Description

Dot1L-IN-7 (compound 25) is a potent and selective disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 of 1.0 μM. Dot1L-IN-7 selectively killed Mixed Lineage Leukemia (MLL)-AF9 without showing any effect on the growth of E2A-HLF cells[1].

IC50 & Target[1]

DOT1L

1 μM (IC50)

Molecular Weight

461.52

Formula

C23H27N9O2

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Dot1L-IN-7
Cat. No.:
HY-146724
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