MYEF2 - myelin expression factor 2 Gene

Also Known as MEF-2; MST156; myEF-2; MSTP156; HsT18564

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 50804

About MYEF2

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:48,134,632-48,178,295 (from NCBI)

This gene has 16 transcripts (splice variants), 221 orthologues and 1 paralogue. Broad expression in brain (RPKM 7.4), testis (RPKM 5.4) and 22 other tissues.

Summary

Enables RNA binding activity. Involved in myotube differentiation and neuron differentiation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

MYEF2 Products (2)

mRNA Protein Name
NM_001301210.2 NP_001288139.2 myelin expression factor 2 isoform b
NM_016132.5 NP_057216.3 myelin expression factor 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in myotube differentiation IEP
IEP: Inferred from expression pattern
8455629 GOA
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
8455629 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in nucleus IDA
IDA: Inferred from direct assay
8455629 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MYEF2 Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (102 - 171)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (235 - 303)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (525 - 592)

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Protein Preferred Names Protein Names

myelin expression factor 2

  • myelin gene expression factor 2

Related Diseases

Diseases Alias
Albinism, Oculocutaneous, Type Vi

  • OCA6

  • Oculocutaneous Albinism Type 6

  • Oculocutaneous Albinism Type Vi

  • Albinism, Oculocutaneous, 6
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Oculocutaneous Albinism

  • Albinism, Oculocutaneous

  • Oca

  • Albinism Oculocutaneous

  • Oca - [Oculocutaneous Albinism]
Brain Malformations With Or Without Urinary Tract Defects

  • Chromosome 1p32-P31 Deletion Syndrome

  • Nfia-Related Disorder

  • Chromosome 1, Monosomy 1p32

  • BRMUTD

  • 1p31p32 Microdeletion Syndrome

  • Nfia Haploinsufficiency

  • Del(1)(P31p32)

  • Monosomy 1p31p32

  • Nfia-Related Disorders
Mitochondrial Complex Ii Deficiency

  • Isolated Mitochondrial Respiratory Chain Complex Ii Deficiency

  • Isolated Succinate-Coenzyme Q Reductase Deficiency

  • Isolated Succinate-Coq Reductase Deficiency

  • Isolated Succinate-Ubiquinone Reductase Deficiency

  • Mitochondrial Respiratory Chain Complex Ii Deficiency

  • Complex 2 Mitochondrial Respiratory Chain Deficiency

  • Succinate Coq Reductase Deficiency

  • Succinate Dehydrogenase Deficiency

  • Isolated Succinate Dehydrogenase Deficiency

  • Succinate-Coenzyme Q Reductase Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08890 MYEF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MYEF2 MGD MGI:104592
Macaca mulatta MYEF2 VGNC VGNC:74983
Rattus norvegicus MYEF2 RGD RGD:1306547
Bos taurus MYEF2 VGNC VGNC:31791
Canis familiaris MYEF2 VGNC VGNC:49714
Felis catus MYEF2 VGNC VGNC:63674
Others MYEF2 NCBI