PARPBP - PARP1 binding protein Gene

Also Known as AROM; PARI; C12orf48

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55010

About PARPBP

Cytogenetic location: 12q23.2 Genomic coordinates (GRCh38): 12:102,120,183-102,197,520 (from NCBI)

Broad expression in bone marrow (RPKM 2.3), testis (RPKM 1.7) and 22 other tissues.

Summary

Predicted to enable DNA binding activity. Involved in negative regulation of double-strand break repair via homologous recombination. Located in chromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PARPBP Products (72)

mRNA Protein Name
NM_001319988.2 NP_001306917.1 PCNA-interacting partner isoform 1
NM_001319993.2 NP_001306922.1 PCNA-interacting partner isoform 3
NM_001319994.2 NP_001306923.1 PCNA-interacting partner isoform 3
NM_001319995.3 NP_001306924.1 PCNA-interacting partner isoform 4
NM_001319996.2 NP_001306925.1 PCNA-interacting partner isoform 5
NM_001382721.1 NP_001369650.1 PCNA-interacting partner isoform 6
NM_001382722.1 NP_001369651.1 PCNA-interacting partner isoform 7
NM_001382723.1 NP_001369652.1 PCNA-interacting partner isoform 8
NM_001382724.1 NP_001369653.1 PCNA-interacting partner isoform 9
NM_001382725.1 NP_001369654.1 PCNA-interacting partner isoform 10
NM_001382726.1 NP_001369655.1 PCNA-interacting partner isoform 11
NM_001382728.1 NP_001369657.1 PCNA-interacting partner isoform 12
NM_001382729.1 NP_001369658.1 PCNA-interacting partner isoform 13
NM_001382731.1 NP_001369660.1 PCNA-interacting partner isoform 14
NM_001382732.1 NP_001369661.1 PCNA-interacting partner isoform 15
NM_001382735.1 NP_001369664.1 PCNA-interacting partner isoform 16
NM_001400853.1 NP_001387782.1 PCNA-interacting partner isoform 17
NM_001400854.1 NP_001387783.1 PCNA-interacting partner isoform 18
NM_001400855.1 NP_001387784.1 PCNA-interacting partner isoform 19
NM_001400856.1 NP_001387785.1 PCNA-interacting partner isoform 20
NM_001400857.1 NP_001387786.1 PCNA-interacting partner isoform 21
NM_001400858.1 NP_001387787.1 PCNA-interacting partner isoform 22
NM_001400859.1 NP_001387788.1 PCNA-interacting partner isoform 23
NM_001400860.1 NP_001387789.1 PCNA-interacting partner isoform 23
NM_001400861.1 NP_001387790.1 PCNA-interacting partner isoform 23
NM_001400862.1 NP_001387791.1 PCNA-interacting partner isoform 24
NM_001400863.1 NP_001387792.1 PCNA-interacting partner isoform 25
NM_001400864.1 NP_001387793.1 PCNA-interacting partner isoform 26
NM_001400865.1 NP_001387794.1 PCNA-interacting partner isoform 27
NM_001400866.1 NP_001387795.1 PCNA-interacting partner isoform 28
NM_001400867.1 NP_001387796.1 PCNA-interacting partner isoform 29
NM_001400868.1 NP_001387797.1 PCNA-interacting partner isoform 30
NM_001400869.1 NP_001387798.1 PCNA-interacting partner isoform 12
NM_001400870.1 NP_001387799.1 PCNA-interacting partner isoform 12
NM_001400871.1 NP_001387800.1 PCNA-interacting partner isoform 12
NM_001400872.1 NP_001387801.1 PCNA-interacting partner isoform 32
NM_001400873.1 NP_001387802.1 PCNA-interacting partner isoform 33
NM_001400874.1 NP_001387803.1 PCNA-interacting partner isoform 34
NM_001400875.1 NP_001387804.1 PCNA-interacting partner isoform 35
NM_001400876.1 NP_001387805.1 PCNA-interacting partner isoform 36
NM_001400877.1 NP_001387806.1 PCNA-interacting partner isoform 37
NM_001400878.1 NP_001387807.1 PCNA-interacting partner isoform 38
NM_001400879.1 NP_001387808.1 PCNA-interacting partner isoform 39
NM_001400880.1 NP_001387809.1 PCNA-interacting partner isoform 40
NM_001400881.1 NP_001387810.1 PCNA-interacting partner isoform 41
NM_001400883.1 NP_001387812.1 PCNA-interacting partner isoform 42
NM_001400884.1 NP_001387813.1 PCNA-interacting partner isoform 43
NM_001400885.1 NP_001387814.1 PCNA-interacting partner isoform 44
NM_001400886.1 NP_001387815.1 PCNA-interacting partner isoform 45
NM_001400887.1 NP_001387816.1 PCNA-interacting partner isoform 46
NM_001400888.1 NP_001387817.1 PCNA-interacting partner isoform 46
NM_001400889.1 NP_001387818.1 PCNA-interacting partner isoform 46
NM_001400890.1 NP_001387819.1 PCNA-interacting partner isoform 47
NM_001400891.1 NP_001387820.1 PCNA-interacting partner isoform 48
NM_001400892.1 NP_001387821.1 PCNA-interacting partner isoform 49
NM_001400893.1 NP_001387822.1 PCNA-interacting partner isoform 49
NM_001400894.1 NP_001387823.1 PCNA-interacting partner isoform 49
NM_001400895.1 NP_001387824.1 PCNA-interacting partner isoform 49
NM_001400896.1 NP_001387825.1 PCNA-interacting partner isoform 50
NM_001400897.1 NP_001387826.1 PCNA-interacting partner isoform 51
NM_001400902.1 NP_001387831.1 PCNA-interacting partner isoform 52
NM_001400903.1 NP_001387832.1 PCNA-interacting partner isoform 53
NM_001400904.1 NP_001387833.1 PCNA-interacting partner isoform 54
NM_001400905.1 NP_001387834.1 PCNA-interacting partner isoform 54
NM_001400906.1 NP_001387835.1 PCNA-interacting partner isoform 55
NM_001400907.1 NP_001387836.1 PCNA-interacting partner isoform 61
NM_001400925.1 NP_001387854.1 PCNA-interacting partner isoform 56
NM_001400926.1 NP_001387855.1 PCNA-interacting partner isoform 57
NM_001400927.1 NP_001387856.1 PCNA-interacting partner isoform 5
NM_001400928.1 NP_001387857.1 PCNA-interacting partner isoform 59
NM_001400929.1 NP_001387858.1 PCNA-interacting partner isoform 60
NM_017915.5 NP_060385.3 PCNA-interacting partner isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
22153967 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of double-strand break repair via homologous recombination IMP
IMP: Inferred from mutant phenotype
22153967 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in chromatin IDA
IDA: Inferred from direct assay
22153967 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PCNA-interacting partner

Related Diseases

Diseases Alias
Frozen Shoulder

  • Adhesive Capsulitis Of Shoulder

  • Bursitis

  • Adhesions-Capsulitis,Shoulder

  • Pericapsulitis Of Shoulder

  • Duplay Bursitis

  • Adhesive Shoulder Peritendinitis

  • Subscapular Adhesion

  • Shoulder Adhesion

  • Adhesive Enthesopathy Of Shoulder Region

  • Adhesive Peritendinitis

  • Adhesive Shoulder Tenosynovitis

  • Duplay Periarthritis

  • Adhesive Shoulder Tendinitis
Shoulder Impingement Syndrome

  • Impingement Syndrome Of Shoulder Region

  • Subacromial Impingement
Patellar Tendinitis

  • Patellar Tendonitis
Spastic Hemiplegia

  • Spastic Hemiplegic Cerebral Palsy

  • Hemiplegic Cerebral Palsy

  • Congenital Hemiplegia

  • Hemiplegic Infantile Cerebral Palsy

  • Cerebral Palsy Spastic Hemiplegic

  • Spastic Hemiplegia Cerebral Palsy

  • Hemiplegia, Spastic
Bursitis

  • Bursitis, Not Otherwise Specified

  • Inflammation Of Bursa
Postpoliomyelitis Syndrome

  • Postpolio Syndrome

  • Post-Polio Syndrome

  • Post Polio Syndrome

  • Polio Late Effects

  • Post-Polio Muscular Atrophy

  • Post-Polio Sequelae

  • Post-Poliomyelitic Syndrome

  • Postpolio Sequelae

  • Postpoliomyelitic Syndrome

  • Postpoliomyelitis Sequelae
Reflex Sympathetic Dystrophy

  • Algodystrophy

  • Reflex Sympathetic Dystrophy Syndrome

  • Complex Regional Pain Syndrome Type 1

  • Complex Regional Pain Syndromes

  • Algodystrophic Syndrome
Myofascial Pain Syndrome

  • Myofascial Pain Syndromes

  • Myofascial Pain Dysfunction Syndrome

  • Fibromyalgia
Plantar Fasciitis

  • Fasciitis, Plantar
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS10072 PARPBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PARPBP MGD MGI:1922567
Macaca mulatta PARPBP VGNC VGNC:75682
Felis catus PARPBP VGNC VGNC:64043
Canis familiaris PARPBP VGNC VGNC:44267
Bos taurus PARPBP VGNC VGNC:32588
Rattus norvegicus PARPBP RGD RGD:2314264
Others PARPBP NCBI