Apba1 - amyloid beta precursor protein binding family A member 1 Gene

Also Known as Mint1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83589

Summary

Enables PDZ domain binding activity; amyloid-beta binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in chemical synaptic transmission and regulation of synaptic vesicle exocytosis. Predicted to act upstream of or within several processes, including amino acid transport; in utero embryonic development; and intracellular protein transport. Located in dendritic spine and plasma membrane. Part of protein-containing complex. Orthologous to human APBA1 (amyloid beta precursor protein binding family A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Apba1 Products (1)

mRNA Protein Name
NM_031779.3 NP_113967.2 amyloid-beta A4 precursor protein-binding family A member 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
15024025 RGD
enables amyloid-beta binding IPI
IPI: Inferred from physical interaction
12196555 RGD
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
9395480 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9395480 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
17084383 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
9395480 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in dendritic spine IDA
IDA: Inferred from direct assay
25378388 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
9395480 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amyloid-beta A4 precursor protein-binding family A member 1

  • adapter protein X11alpha

  • amyloid beta (A4) precursor protein-binding, family A, APBA1: amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)

  • amyloid beta (A4) precursor protein-binding, family A, member 1

  • mint-1

  • neuron-specific X11 pro

Apba1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Apba1 O35430 Stxbp1 Rattus norvegicus P61765
Anti Bait CoIP
9395480
Intra
Apba1 O35430 Stxbp1 Rattus norvegicus P61765
Pull Down
9395480
Intra
Apba1 O35430 Stx1a Rattus norvegicus P32851
Pull Down
9395480
Intra
Apba1 O35430 Stx1a Rattus norvegicus P32851
Pull Down
16763567
Intra
Apba1 O35430 Stx1a Rattus norvegicus P32851
Anti Bait CoIP
9395480
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00802 APBA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W751932 Carboxy-EG6-undecanethiol / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apba1 NCBI NCBI:320