Chivosazol A, a new inhibitor of eukaryotic organisms isolated from myxobacteria
- J Antibiot (Tokyo). 1995 Sep;48(9):962-6. doi: 10.7164/antibiotics.48.962.
Affiliations
- 1. GBF, Gesellschaft für Biotechnologische Forschung, Departments of Biology of Natural Products, Braunschweig, Germany.
PMID: 7592063
DOI: 10.7164/antibiotics.48.962
Abstract
A new Antibiotic, chivosazol, was isolated from the culture broth of the myxobacterium Sorangium cellulosum strain So ce12. It is a macrocyclic ring with one oxazol ring and a glycosidically bound 6-deoxyglucose (quinovose) at C-11. The Antibiotic shows antimicrobial activity against yeasts and filamentous fungi, and is especially potent against mammalian cells. It was not active against bacteria.
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