ATP4A - ATPase H+/K+ transporting subunit alpha Gene

Also Known as ATP6A

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 495

About ATP4A

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,550,031-35,563,658 (from NCBI)

This gene has 4 transcripts (splice variants), 183 orthologues, 21 paralogues and is associated with 1 phenotype. Restricted expression toward stomach (RPKM 218.2).

Summary

The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a Proton Pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]

ATP4A Products (1)

mRNA	Protein	Name
NM_000704.3	NP_000695.2	potassium-transporting ATPase alpha chain 1

ATP4A Protein Structure

H-K_ATPase_N

Cation_ATPase_N

E1-E2_ATPase

Hydrolase

Cation_ATPase_C

0
200
400
600
800
1035 a.a.

Protein Preferred Names	Protein Names
potassium-transporting ATPase alpha chain 1	ATPase H+/K+ transporting alpha subunit

Related Diseases

Diseases	Alias
Familial Gastric Type 1 Neuroendocrine Tumor
Peptic Esophagitis	Reflux Esophagitis Peptic Reflux Disease Reflux Oesophagitis Esophagitis, Peptic Gastro-Esophageal Reflux Disease With Esophagitis
Hernia, Hiatus	Hiatal Hernia Hiatus Hernia Diaphragmatic - Hiatus -Hernia Hernia, Hiatal
Active Peptic Ulcer Disease	Gi Bleeding Active Peptic Ulcer Gastrointestinal Hemorrhage
Chronic Laryngitis
Dyskinesia Of Esophagus	Esophageal Motility Disorders Dyskinesia Of Oesophagus Esophageal Dysmotility Esophageal Motility Disorder Oesophageal Dysmotility Oesophageal Motor Disorder Esophageal Spasm
Volvulus Of Midgut	Volvulus Intestinal Volvulus Intestinal Malrotation, Familial Familial Intestinal Malrotation Twist Of Intestine, Bowel, Or Colon
Dieulafoy Lesion	Dieulafoy'S Lesion Dieulafoy Lesion Of Intestine Dieulafoy Lesion Of Stomach And Duodenum Dieulafoy Disease Exulceratio Simplex Dieulafoy Dieulafoy'S Vascular Malformation
Lymphocytic Colitis	Colitis, Lymphocytic
Gastroduodenitis
Duodenal Obstruction
Peptic Ulcer Perforation	Perforated Peptic Ulcer Acute Peptic Ulcer With Perforation Peptic Ulcer With Perforation
Aspiration Pneumonitis	Chemical Pneumonitis Mendelson'S Syndrome Aspiration Pneumonia Pneumonitis Due To Fumes And/Or Vapors Toxic Pneumonitis Mendelson'S Syndrome Resulting From A Procedure Mendelson Syndrome Resulting From A Procedure Pulmonary Acid Aspiration Syndrome Pneumonitis Due To Inhalation Of Gastric Secretions Mendelson Syndrome Due To Anaesthesia During Labour And Delivery Inhalation Of Stomach Contents Or Secretions, Nos Due To Anaesthesia During Labour And Delivery
Microscopic Colitis	Colitis, Microscopic
Gastroduodenal Crohn'S Disease	Upper Gi Crohn'S Disease
Lymphocytic Gastritis
Gastrojejunal Ulcer	Acute Gastrojejunal Ulcer With Hemorrhage Acute Gastrojejunal Ulcer With Hemorrhage And Obstruction Acute Gastrojejunal Ulcer With Hemorrhage And Perforation Acute Gastrojejunal Ulcer With Hemorrhage And Perforation, With Obstruction Acute Gastrojejunal Ulcer With Hemorrhage, With Perforation And With Obstruction Acute Gastrojejunal Ulcer With Perforation Acute Gastrojejunal Ulcer With Perforation And Obstruction Acute Gastrojejunal Ulcer With Perforation, With Obstruction Acute Gastrojejunal Ulcer Without Hemorrhage And Without Perforation Acute Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction Acute Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction Acute Gastrojejunal Ulcer, With Hemorrhage, With Obstruction Chronic Gastrojejunal Ulcer Without Hemorrhage And Without Perforation Chronic Gastrojejunal Ulcer Without Hemorrhage, Without Perforation And Without Obstruction Chronic Gastrojejunal Ulcer Without Mention Of Hemorrhage Or Perforation, Without Mention Of Obstruction Marginal Ulcer
Aspiration Pneumonia	Pneumonia, Aspiration Pneumonia Aspiration Aspiration Pneumonitis
Toxic Megacolon	Megacolon, Toxic Toxic Dilatation Of Colon Toxic Functional Megacolon
Autoimmune Gastritis
Superior Mesenteric Artery Syndrome	Wilkie Syndrome Wilkie'S Syndrome Arteriomesenteric Duodenal Compression Syndrome Cast Syndrome Vascular Compression Of The Duodenum Smas Arteriomesenteric Compression Of Duodenojejunal Flexure
Blind Loop Syndrome	Bacterial Overgrowth Syndrome
Gastric Dilatation	Stomach Dilatation
Esophageal Candidiasis	Candidiasis Of The Esophagus Candida Esophagitis Candidal Esophagitis Esophageal Moniliasis Esophageal Thrush
Esophagitis, Eosinophilic, 1	Eosinophilic Esophagitis EOE1 Esophagitis, Eosinophilic Ee
Chronic Intestinal Vascular Insufficiency	Chronic Mesenteric Ischemia Cmi - Chronic Mesenteric Ischaemia
Internal Hemorrhoid	Internal Hemorrhoids
Rumination Disorder	Rumination Syndrome Psychogenic Rumination Rumination Disorders
Median Arcuate Ligament Syndrome	Celiac Artery Compression Syndrome Dunbar Syndrome Mals Harjola-Marable Syndrome Marable'S Syndrome Celiac Axis Syndrome
Granulomatous Gastritis
Bile Reflux
Gastric Hemangioma	Hemangioma Of Stomach
Hemorrhoid	Hemorrhoids Hemorrhoidal Disease Rectal Diseases Piles Unspecified Haemorrhoids Without Complication
Acquired Gastric Outlet Stenosis	Adult Hypertrophic Pyloric Stenosis Acquired Hypertrophic Pyloric Stenosis
Gastric Lymphoma	Familial Primary Gastric Lymphoma Lymphoma Of The Stomach Primary Gastric Lymphoma
Ischemic Colitis	Colitis, Ischemic Irreversible Ischaemic Colitis
Clostridium Difficile Colitis	Pseudomembranous Colitis Colitis Pseudomembranous Enterocolitis, Pseudomembranous Pseudomembranous Enterocolitis Clostridium Difficile Infection
Gastritis, Familial Giant Hypertrophic	Menetrier Disease Gastric Mucosal Hypertrophy Giant Hypertrophic Gastritis Hypertrophic Gastropathy Gastritis, Hypertrophic Familial Giant Hypertrophic Gastritis Giant Rugal Hypertrophy Of Stomach Hypertrophic Gastritis Gastroenteropathy, Protein Losing Giant Hypertrophic Gastropathy Giant Hypertrophy Of The Gastric Mucosa Hypoproteinemic Hypertrophic Gastropathy Menetrier'S Disease Giant Hypertrophic Hypersecretory Gastritis
Fungal Esophagitis
Bacterial Esophagitis
Duodenitis	Hemorrhagic Duodenitis Acute Enteritis Of The Mouse Intestinal Tract Nonspecific Duodenitis Inflammation Of Duodenum Dodecadactylitis Duodenal Inflammation Peptic Duodenitis
Collagenous Colitis	Colitis, Collagenous Microscopic Colitis, Collagenous Type
Beta-Lactam Allergy
Functional Gastric Disease
Peptic Ulcer Disease	Peptic Ulcer Acute Peptic Ulcer With Hemorrhage Acute Peptic Ulcer With Hemorrhage And Perforation Acute Peptic Ulcer Without Hemorrhage And Without Perforation
Necrotizing Gastritis
Gastric Antral Vascular Ectasia	Watermelon Stomach Gave
Gastritis	Acute Gastric Mucosal Erosion Erosive Gastritis Erosive Gastropathy Gastritis Erosive Idiopathic Erosive/Hemorrhagic Gastritis Inflammation Of Gastric Mucosa Gastroduodenitis Gastritis Nos Noninfectious Gastroenteritis Nonbacterial Gastroenteritis Of Infant Acute Gastric Infection Acute Simple Gastritis Chronic Antral Gastritis Chronic Fundal Gastritis Chronic Simple Gastritis Acute Gastroduodenitis Acute Antral Gastritis Acute Erosive Gastritis Bile Reflux Gastritis Gastritis Due To Biliary Reflux
Angiodysplasia Of Intestine
Persistent Moderate Asthma
Eosinophilic Gastritis	Eosinophilic Enteropathy
Duodenum Disease	Duodenal Diseases Duodenal Disease Duodenum Disorder
Laryngitis	Acute Laryngitis
Pancreatic Vasoactive Intestinal Peptide Producing Tumor	Pancreatic Vasoactive Intestinal Peptide Producing Tumour Pancreatic Vip Producing Tumor Pancreatic Vip Producing Tumour Pancreatic Vipoma
Acquired Laryngomalacia
Mediastinitis
Esophageal Varix	Esophageal Varices Bleeding Esophageal Varices Bleeding Oesophageal Varices Esophageal Varices In Disease Classified Elsewhere, With Bleeding Esophageal Varices With Bleeding Esophageal Varices With Bleeding In Disease Ec Esophageal Varices Without Bleeding Esophageal Varices Without Mention Of Bleeding
Vitamin Metabolic Disorder
Pernicious Anemia	Anemia, Pernicious Anemia Pernicious Pernicious Anaemia Addison'S Anaemia Biermer'S Anaemia Biermer'S Anemia Acquired Pernicious Anemia Addison-Biermer Anemia Addisonian Anemia Biermer Anemia Biermer'S Disease Juvenile Onset Pernicious Anemia Biermer Disease Biermer-Addison Disease
Lingual Goiter
Benign Shuddering Attacks	Shuddering Attacks
Polyposis, Skin Pigmentation, Alopecia, And Fingernail Changes	Cronkhite-Canada Syndrome Gastric Cronkhite Canada Polyposis Cronkhite-Canada Disease Polyposis Skin Pigmentation Alopecia Fingernail Changes Gastrointestinal Polyposis-Ectodermal Changes Syndrome Gastrointestinal Polyposis-Skin Pigmentation-Alopecia-Fingernail Changes Syndrome Polyposis, Gastrointestinal, With Ectodermal Changes
Scalp Dermatosis	Scalp Dermatoses Dermatosis Of Scalp
Zollinger-Ellison Syndrome	Gastrinoma Pancreatic Ulcerogenic Tumor Syndrome Z E Syndrome Zes Ze - [Zollinger-Ellison] Syndrome
Esophageal Disease	Esophageal Diseases Esophageal Ulcer Esophageal Disorder Ulcer Of Esophagus
Drug Allergy	Allergy Drug Drug Allergies
Cough Variant Asthma
Angiodysplasia	Angiodysplasia Of Colon Angiodysplasia Of Stomach And Duodenum With Hemorrhage Angiodysplasia Of Large Intestine Telangiectasia Of Colon Vascular Ectasia Of Colon Av - [Angiodysplasia Malformation Of Colon] Colon Angiodysplasia Colonic Angiodysplasia Vascular Ectasia Of Large Intestine
Vitamin B12 Deficiency	Cobalamin Deficiency Hypocobalaminemia Vitamin B 12 Deficiency Cyanocobalamin Deficiency Deficiency Of Vitamin B12
Eosinophilic Gastroenteritis	Eosinophilic Enteritis Ege Eosinophilic Gastroenterocolitis Eosinophilic Esophagitis Eosinophilic Gastritis Eosinophilic Gastroenteropathy Gastroenteritis, Eosinophilic Eosinophilic Enteropathy
Afferent Loop Syndrome	Afferent Limb Syndrome
Viral Esophagitis
Paralytic Ileus	Adynamic Ileus Paralytic Ileus Of Bowel Ileus Nos Paralysis Of Bowel Paralysis Of Intestine Adynamic Intestinal Obstruction Paralytic Intestinal Ileus
Duodenogastric Reflux
Pancreatic Gastrinoma	Pancreatic G-Cell Tumor
Esophageal Diverticulosis	Diverticulosis, Esophageal
Duodenal Gastrinoma	Duodenal G-Cell Gastrin Producing Tumor Gastrinoma Of Duodenum Malignant Duodenal Gastrinoma Duodenal Gastrin-Producing Neuroendocrine Tumor
Vein Disease	Disorder Of Vein
Interstitial Nephritis	Nephritis, Interstitial Renal Tubulo-Interstitial Disease Nephritis Interstitial Nephritis, Tubulointerstitial
Megaesophagus	Esophageal Achalasia
Penicillin Allergy	Allergy To Penicillin
Endosteal Hyperostosis, Autosomal Dominant	Osteosclerosis Worth Syndrome Osteosclerosis, Autosomal Dominant Hyperostosis, Endosteal Endosteal Hyperostosis, Worth Type Worth Disease Autosomal Dominant Endosteal Hyperostosis Autosomal Dominant Osteosclerosis, Worth Type Hyperostosis Corticalis Generalisata, Benign Form Of Worth, With Torus Palatinus Autosomal Dominant Osteosclerosis Benign Form Of Worth Hyperostosis Corticalis Generalisata With Torus Platinus Worth'S Syndrome Worth Type Autosomal Dominant Osteosclerosis Hyperostosis Corticalis Generalisata, Benign Form Of Worth With Torus Palatinus Osteosclerosis, Autosomal Dominant, Worth Type WENHY Endosteal Hyperostosis Autosomal Dominant Hyperostosis Corticalis Generalisata Benign Form Of Worth With Torus Palatinus Osteosclerosis Autosomal Dominant Acquired Osteosclerosis
Lactose Intolerance	Lactose Malabsorption Lm - Lactose Malabsorption Alactasia Dairy Product Intolerance Hypolactasia Milk Sugar Intolerance Cow Milk Enteropathy Intolerance Or Malabsorption Of Lactose Lm - [Lactose Malabsorption] Milk Intolerance
Gastric Gastrinoma	Gastric G-Cell Gastrin Producing Tumor Gastric Gastrin-Producing Neuroendocrine Tumor
Functional Diarrhea	Functional Diarrhoea
Squamous Papillomatosis
Pneumatosis Cystoides Intestinalis
Displacement Of Cardia Through Esophageal Hiatus	Congenital Hiatus Hernia Congenital Hiatal Hernia Congenital Displacement Of Cardia Through Oesophageal Hiatus Congenital Hiatus Oesophageal Hernia Congenital Paraoesophageal Hernia Congenital Sliding Hiatal Hernia Congenital Oesophageal Hiatal Hernia
Postgastrectomy Syndrome	Postgastrectomy Syndromes Postgastric Surgery Syndrome
Esophagus Adenocarcinoma	Esophageal Adenocarcinoma Oesophageal Adenocarcinoma Adenocarcinoma Of Esophagus Adenocarcinoma Of The Esophagus
Meckel Diverticulum	Meckel'S Diverticulum Persistent Vitelline Duct
Acute Laryngitis	Acute Laryngitis Nos Laryngeal Inflammation Laryngitis Nos Larynx Inflammation
Pylorospasm
Laryngeal Tuberculosis	Tuberculosis, Laryngeal
Benzylpenicillin Allergy	Benzyl Penicillin Allergy Penicillin G Allergy
Barrett'S Adenocarcinoma	Barrett Adenocarcinoma Adenocarcinoma Arising In Barrett'S Mucosa
Tracheomalacia	Congenital Tracheomalacia Congenital Major Airway Collapse Tracheomalacia, Congenital Type 1 Tracheomalacia
Microinvasive Gastric Cancer	Early Gastric Cancer Surface Gastric Cancer
Biliary Dyskinesia	Sphincter Of Oddi Dysfunction
Fungal Gastritis
Diclofenac Allergy	Voltaren Allergy
Tracheal Disease	Tracheal Diseases Tracheal Anomaly Tracheal Disorders
Intestinal Perforation	Perforation Of Intestine
Atrophic Gastritis	Gastritis, Atrophic Gastric Atrophy Gastritis Atrophic
Common Bile Duct Disease	Common Bile Duct Diseases
Emphysematous Cholecystitis	Gaseous Pericholecystitis
Chronic Duodenal Ileus
Atrophic Glossitis	Atrophy Of Tongue Papillae Glossitis, Hunter'S Hunter'S Glossitis Smooth Atrophic Tongue Hunter Glossitis Central Papillary Atrophy Of The Tongue
Cascade Stomach	Hourglass Stricture Or Stenosis Of Stomach Hourglass Contraction Of Stomach Hourglass Stenosis Of Stomach Hourglass Stricture Of Stomach
Gastrointestinal Neuroendocrine Benign Tumor
Cecal Disease	Cecal Diseases Disorder Of Cecum
Splenic Artery Aneurysm	Aneurysm Of Splenic Artery
Glossitis	Inflammation Of Tongue Tongue Inflammation Glazed Tongue
Myopathy, X-Linked, With Excessive Autophagy	X-Linked Myopathy With Excessive Autophagy Xmea MEAX Vacuolar Myopathy
Diverticulitis
Bacterial Gastritis
Rectal Disease	Rectal Diseases Rectal Disorders
Bacterial Pneumonia	Gram-Negative Pneumonia Pneumonia Due To Other Gram-Negative Bacteria Pneumonia Bacterial Pneumonia, Bacterial Acute Bacillus Pneumonia Acute Bacterial Pneumonia Bacillus Double Pneumonia Bacillus Pneumonia Bacteria Pneumonia Bacterial Double Pneumonia Bacterial Lobar Pneumonia Bacterial Purulent Pneumonia Bronchopneumonia Due To Bacteria Other Than S. Pneumoniae And H. Influenzae
Gastric Neuroendocrine Neoplasm	Gastric Neuroendocrine Tumor Neuroendocrine Tumor Of The Stomach Neuroendocrine Tumor Of Stomach Gnet Gastric Net Net Of Stomach
Giardiasis	Beaver Feaver Infection By Giardia Lamblia Lambliasis Giardia Lamblia Dysentery Giardial Diarrhoea Lamblia Dysentery Giardia Duodenalis Dysentery Giardia Intestinalis Dysentery
Hypothyroidism	Thyroid Diseases Thyroid Disease Thyroid Deficiency Thyroid Insufficiency Dysfunction Thyroid Thyroid Dysfunction
Intestinal Obstruction	Inspissated Milk Syndrome Milk Curd Syndrome
Barrett Esophagus	Barrett'S Esophagus Barrett Esophagus/Esophageal Adenocarcinoma Barrett Metaplasia Barrett'S Ulcer Of Esophagus Ulcerative Esophagitis Barrett'S Esophagus With Esophagitis Barrett'S Oesophagus Barretts Syndrome Barrett Syndrome BE Peptic Ulcer Of Esophagus Adenocarcinoma Of Esophagus
Cardia Cancer	Ca Cardia - Stomach Malignant Neoplasm Of Cardia Of Stomach
Laryngomalacia	Congenital Laryngomalacia Congenital Laryngeal Stridor Laryngomalacia Congenital Floppy Epiglottis
Choledocholithiasis
Deficiency Anemia	Anemia Deficiency Anemias Anaemia
Somatoform Disorder	Physiological Malfunction Arising From Mental Factor Psychosomatic Disorder Psychophysiologic Disorders
Iron Deficiency Anemia	Iron-Deficiency Anemia Fe Deficiency Anaemia Ida - [Iron Deficiency Anemia] Fe - [Iron] Deficiency Anemia Nos
Osmotic Diarrhea
Cervix Erosion	Erosion Of Cervix Uterine Cervical Erosion
Pyuria	Pus Cells In Urine
Esophagus Melanoma	Melanoma Of Esophagus Melanoma Of Oesophagus Oesophagus Melanoma Esophageal Melanoma
Achalasia	Cardiospasm Achalasia Of Cardia Esophageal Achalasia Hypertensive Lower Esophageal Sphincter Idiopathic Achalasia Achalasia Cardia Idiopathic Achalasia Of Esophagus Primary Achalasia Achalasia Of Esophagus Lack Of Reflex Relaxation Of Lower Oesophageal Sphincter Aperistalsis Of The Oesophagus Achalasia Of Oesophagus Oesophageal Achalasia Achalasia Nos Cardia Spasm Cardia Achalasia Oesophageal Cardiospasm Oesophagus Achalasia Reflex Cardiospasm
Central Nervous System Origin Vertigo	Vertigo Of Central Origin Vertigo Central Vestibular Vertigo
Marginal Zone B-Cell Lymphoma	Marginal Zone Lymphoma Mzl Mucosa-Associated Lymphoid Tissue Lymphoma
Atrial Septal Defect 8	ASD8 Atrial Heart Septal Defect 8 Septal Defect, Atrial, Type 8
Lymphoma, Mucosa-Associated Lymphoid Type	Malt Lymphoma Gastric Lymphoma, Primary Lymphoma, Malt, Somatic Mucosa-Associated Lymphoid Tissue Lymphoma Extranodal Marginal Zone B-Cell Lymphoma MALTOMA Marginal Zone B-Cell Lymphoma Mucosa-Associated Lymphatic Tissue Lymphoma Primary Gastric Lymphoma Gastric Lymphoma Familial Primary Gastric Lymphoma
Dysentery	Infectious Diarrhea
Chlorhexidine Allergy
Esophageal Leukoplakia	Leukoplakia Of Esophagus
Hepatic Vascular Disease	Vascular Disorder Of Liver
Abdominal Tuberculosis
X-Linked Chondrodysplasia Punctata 1	Chondrodysplasia Punctata 1, X-Linked Arylsulfatase E Deficiency Chondrodystrophia Calcificans Congenita Cdpx1 X-Linked Recessive Chondrodysplasia Punctata 1 Brachytelephalangic Chondrodysplasia Punctata
Angular Cheilitis	Cheilosis Angular Cheilosis Angular Stomatitis Commissural Cheilitis
Gastroesophageal Reflux	Gastroesophageal Reflux Disease Gerd GER Gastroesophageal Reflux, Pediatric Acid Reflux Gastresophageal Reflux Gastro-Esophageal Reflux Gerd - Gastro-Esophageal Reflux Disease
Anus Disease	Anal Fissure Ulcer Of Anus Anus Diseases Anal Disease Anal Fissure And Fistula Anal Ulcer Fissure In Ano Nontraumatic Tear Of Anus Solitary Anal Ulcer Abnormality Of The Anus Anal Disorders Ulcer Of Anus And Rectum Solitary Ulcer Of Anus Stercoral Ulcer Of Anus
Nutritional Deficiency Disease	Malnutrition Nutritional Disorder Nutritional Deficiency Nutrition Deficiency Diseases Carbamoyl-Phosphate Synthase I Deficiency Disease Nutrition Disorders
Cefuroxime Allergy	Cephuroxime Allergy Zinacef Allergy
Apnea, Obstructive Sleep	Obstructive Sleep Apnea Syndrome Obstructive Sleep Apnea Sleep Apnea, Obstructive Osa Osas Sleep Apnea/Hypopnea Syndrome Sahs Upper Airway Resistance Sleep Apnea Syndrome Apnea, Obstructive Obstructive Apnea Osahs Sleep Apnea Hypopnea Syndrome Sleep Apnea Syndrome, Obstructive Sleep Apnea Obstructive Sleep Apnea Syndromes Obstructive Sleep Apnoea Syndrome Obstructive Sleep Apnoea, Adult Osa - [Obstructive Sleep Apnoea] Obstructive Sleep Apnoea, Paediatric Obstructive Sleep Apnoea Hypopnoea Syndrome Osa Syndrome Sleep Apnoea Nos [Sas] - Sleep Apnoea Syndrome Sleep Apnoea Syndrome [Osahs] - Obstructive Sleep Apnoea-Hypopnea Syndrome [Sahs] - Sleep Apnoea-Hypopnea Syndrome
Acute Cholangitis
Paine Syndrome	Pain Disorder Pain Microcephaly With Spastic Diplegia Pain Syndrome
Prostatic Hypertrophy	Benign Prostatic Hypertrophy Prostatic Hyperplasia
Megaloblastic Anemia	Imerslund-Grasbeck Syndrome Igs Defect Of Enterocyte Intrinsic Factor Receptor Enterocyte Cobalamin Malabsorption Familial Megaloblastic Anemia Megaloblastic Anemia 1 Selective Cobalamin Malabsorption With Proteinuria Imerslund-Gräsbeck Syndrome Anemia, Megaloblastic Grasbeck-Imerslund Syndrome Megaloblastic Anaemia Mga1 Norwegian Type Recessive Hereditary Megaloblastic Anaemia 1 Recessive Hereditary Megaloblastic Anemia 1 Rh-Mga1 Gräsbeck-Imerslund Disease Pernicious Anemia, Juvenile, Due To Selective Intestinal Malabsorption Of Vitamin B12, With Proteinuria Juvenile Pernicious Anemia With Proteinuria Due To Selective Intestinal Malabsorption Of Vitamin B12 Anemia Megaloblastic Megaloblastic Anemia Due To Inborn Errors Of Metabolism 3-@Methylglutaconic Aciduria, Type I
Celiac Disease 1	Celiac Disease Coeliac Disease Celiac Sprue Celiac Disease, Susceptibility To Gluten-Sensitive Enteropathy Nontropical Sprue Sprue CELIAC1 Celiac Disease, Susceptibility To, 1 Celiac Sprue 1 Celiac Sprue, Susceptibility To, 1 Gluten-Sensitive Enteropathy 1 Gluten-Sensitive Enteropathy, Susceptibility To, 1 Idiopathic Steatorrhea Cœliac Disease Gluten Intolerance Gluten-Induced Enteropathy Gluten Enteropathy Celiac Disease, Susceptibility To, Type 1 Childhood Celiac Disease Coeliac Rickets Gee Disease Gee-Herter Disease Heubner-Herter Disease Idiopathic Steatorrhoea Thaysen'S Disease Herter Gee Syndrome
Megacolon	Dilatation Of Colon
Barbiturate Abuse
Urinary Tract Infection	Urinary Tract Infections Uti Urinary Tract Infection Nos Uti - [Urinary Tract Infection] Uti Nos - [Urinary Tract Infection Nos] Urosepsis Nos E Coli Uti E Coli Urinary Tract Infection Escherichia Coli Uti
Opportunistic Mycosis	Opportunistic Mycoses Opportunistic Systemic Mycoses
Hypopigmentation Of Eyelid
Fungal Infectious Disease	Mycoses Mycosis
Pelvic Varices	Varix Of Pelvis Pelvic Varicose Vein
Autoimmune Disease Of Gastrointestinal Tract
Cardiomyopathy, Dilated, 1gg	Dilated Cardiomyopathy 1gg CMD1GG Cardiomyopathy, Dilated 1gg Cardiomyopathy, Dilated, Type 1gg
Aggressive Systemic Mastocytosis	Asm Lymphadenopathic Mastocytosis With Eosinophilia
Esophageal Tuberculosis	Tuberculosis Of Esophagus
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Constipation
Heart Conduction Disease	Conduction Disorder Of The Heart Heart Rhythm Disease
Multiple Endocrine Neoplasia, Type I	Multiple Endocrine Neoplasia Type 1 MEN1 Wermer Syndrome Multiple Endocrine Neoplasia 1 Multiple Endocrine Neoplasia, Type 1 Men I Endocrine Adenomatosis, Multiple Mea I Men Type I Wermer'S Syndrome Men1 Syndrome Multiple Endocrine Adenomatosis Endocrine Adenomatosis Multiple Men 1 Familial Multiple Endocrine Neoplasia Type I Neoplasia, Endocrine, Multiple, Type 1 Multiple Endocrine Neoplasia
Esophageal Atresia	Tracheoesophageal Fistula Congenital Atresia Of Esophagus Congenital Imperforate Esophagus Imperforate Esophagus Oesophageal Atresia Te Fistula Tef Tracheoesophageal Fistula With Or Without Esophageal Atresia
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Esophageal Neuroendocrine Tumor	Esophageal Neuroendocrine Tumour Neuroendocrine Tumor Of Esophagus Neuroendocrine Tumour Of Oesophagus
Beach Ear	Acute Swimmer'S Ear Acute Bacterial Inflammation Of External Ear Acute Otitis Externa, Diffuse Acute Swimmers' Ear Tank Ear
Outlet Dysfunction Constipation
Diaphragmatic Hernia, Congenital	Congenital Diaphragmatic Hernia Diaphragmatic Hernia Cdh Congenital Diaphragmatic Defect Hernia, Diaphragmatic Dih Hernia, Congenital Diaphragmatic Hcd Diaphragmatic Defect, Congenital Diaphragm, Unilateral Agenesis Of Hemidiaphragm, Agenesis Of Diaphragmatic Hernia 1 Agenesis Of Hemidiaphragm Unilateral Agenesis Of Diaphragm Hernia Diaphragmatic Hernia Diaphragmatic Congenital Hernia, Diaphragmatic, Type 1 Hiatus Hernia Oesophageal Hiatus Hernia Paraoesophageal Hernia Sliding Hiatus Hernia Congenital Diaphragm Hernia Congenital Diaphragm Defect With Hernia Gross Congenital Diaphragm Defect
Bilirubin Metabolic Disorder	Hyperbilirubinemia Hereditary Hyperbilirubinemia Hyperbilirubinemia, Hereditary Hyperbilirubinaemia
Migraine With Or Without Aura 1	Migraine Migraine With Or Without Aura, Susceptibility To, 1 Migraine Disorder Migraine Variant Migraines Migraine Disorders Mgr1 Mgau Ma Migraine With Or Without Aura Classic Migraine Common Migraine Disorder, Migraine Headache Migraine Headache Migrainous Migraine Headache Migraine Syndrome Headache Including Migraine Migraine, Susceptibility To
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01200	ATP4A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	ATP4A	VGNC	VGNC:58589
Canis familiaris	ATP4A	VGNC	VGNC:38262
Macaca mulatta	ATP4A	VGNC	VGNC:82107
Felis catus	ATP4A	VGNC	VGNC:68640
Mus musculus	ATP4A	MGD	MGI:88113
Rattus norvegicus	ATP4A	RGD	RGD:2177
Others	ATP4A	NCBI