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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
LPCAT1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "LPCAT1" in MCE Product Catalog:
Cat. No.: HY-W140439
CAS No.: 19420-56-5
Synonyms: 18:1 Lyso PC
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1-Oleoyl-sn-glycero-3-phosphocholine (18:1 Lyso PC), a lysophospholipid, is a GPR82 inhibitor. 1-Oleoyl-sn-glycero-3-phosphocholine abrogates constitutive Gi-coupled GPR82 activity, shifts active/inactive equilibrium to inactive, suppresses Gi protein activation, increases cAMP production, and decreases GTPγS binding to Gαi proteins. 1-Oleoyl-sn-glycero-3-phosphocholine contributes to adipocyte lipolysis regulation.1-Oleoyl-sn-glycero-3-phosphocholine exhibits reduced serum levels in mouse models of steatohepatitis, linked to hepatic Lpcat 1-4 up-regulation [1] .
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TSI-01 is a selective LPCAT2 inhibitor, with IC50 values of 0.47 μM and 3.02 μM against LPCAT2 and LPCAT1, respectively. TSI-01 competitively inhibits acetyl-CoA (acetyl-CoA) targeting the lysophosphatidic acid acetyltransferase activity of LPCAT2, and suppresses PAF biosynthesis in calcium ionophore-stimulated mouse peritoneal macrophages. TSI-01 inhibits the proliferation of endometrial cancer cells and promotes endometrial cancer cell apoptosis (apoptosis). TSI-01 can be used for the research of endometrial cancer and PAF-related inflammatory diseases [1] .
Cat. No.: HY-RS18199
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Lpcat1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lpcat1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07764
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LPCAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for LPCAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24675
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Lpcat1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lpcat1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81530A
Synonyms: AYTL2; LPCAT; AGPAT9; PFAAP3; AGPAT10; LPCAT-1; lysoPAFAT
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
