Cap-specific adenosine methyltransferase
Definition:
References:
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[1]. Erdem Sendinc, et al. PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression. Mol Cell. 2019 Aug 8;75(3):620-630.e9. [Content Brief]
[2]. Hanxiao Sun, et al. Cap-specific, terminal N6-methylation by a mammalian m6Am methyltransferase. Cell Res. 2019 Jan;29(1):80-82. [Content Brief]
[3]. Shinichiro Akichika, et al. Cap-specific terminal N 6-methylation of RNA by an RNA polymerase II-associated methyltransferase. Science. 2019 Jan 11;363(6423):eaav0080. [Content Brief]
[4]. Konstantinos Boulias, et al. Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome. Mol Cell. 2019 Aug 8;75(3):631-643.e8. [Content Brief]
[5]. Dan Yu, et al. Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima. J Biol Chem. 2021 Jan-Jun;296:100270. [Content Brief]
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