Dynactin-associated protein

Definition:

Plays a role in the regulation of cell proliferation. Promotes activation of the AKT1 signaling pathway. Promotes phosphorylation of AKT1 at 'Ser-473'.

References:

[1]. Tatsuki Kunoh, et al. A novel human dynactin-associated protein, dynAP, promotes activation of Akt, and ergosterol-related compounds induce dynAP-dependent apoptosis of human cancer cells. Mol Cancer Ther. 2010 Nov;9(11):2934-42. [Content Brief]

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