Dynamin-1-like protein
Definition:
References:
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[1]. Annett Koch, et al. Dynamin-like protein 1 is involved in peroxisomal fission. J Biol Chem. 2003 Mar 7;278(10):8597-605. [Content Brief]
[2]. Hans R Waterham, et al. A lethal defect of mitochondrial and peroxisomal fission. N Engl J Med. 2007 Apr 26;356(17):1736-41. [Content Brief]
[3]. E Smirnova, et al. A human dynamin-related protein controls the distribution of mitochondria. J Cell Biol. 1998 Oct 19;143(2):351-8. [Content Brief]
[4]. Raghav Kalia, et al. Structural basis of mitochondrial receptor binding and constriction by DRP1. Nature. 2018 Jun;558(7710):401-405. [Content Brief]
[5]. Oliver C Losón, et al. Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission. Mol Biol Cell. 2013 Mar;24(5):659-67. [Content Brief]
[6]. Hailong Han, et al. PINK1 phosphorylates Drp1S616 to regulate mitophagy-independent mitochondrial dynamics. EMBO Rep. 2020 Aug 5;21(8):e48686. [Content Brief]
[7]. Hongmei Li, et al. A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis. Nat Cell Biol. 2013 Jul;15(7):773-85. [Content Brief]
[8]. E Smirnova, et al. Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell. 2001 Aug;12(8):2245-56. [Content Brief]
[9]. K Zaha, et al. DNM1L-related encephalopathy in infancy with Leigh syndrome-like phenotype and suppression-burst. Clin Genet. 2016 Nov;90(5):472-474. [Content Brief]
[10]. Xiao-Jian Han, et al. CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphology. J Cell Biol. 2008 Aug 11;182(3):573-85. [Content Brief]
[11]. Karen Schmitt, et al. Circadian Control of DRP1 Activity Regulates Mitochondrial Dynamics and Bioenergetics. Cell Metab. 2018 Mar 6;27(3):657-666.e5. [Content Brief]
[12]. Alessia Nasca, et al. Biallelic Mutations in DNM1L are Associated with a Slowly Progressive Infantile Encephalopathy. Hum Mutat. 2016 Sep;37(9):898-903. [Content Brief]
[13]. Chris Fröhlich, et al. Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein. EMBO J. 2013 May 2;32(9):1280-92. [Content Brief]
[14]. Dong-Hyung Cho, et al. S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury. Science. 2009 Apr 3;324(5923):102-5. [Content Brief]
[15]. Naoko Taguchi, et al. Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J Biol Chem. 2007 Apr 13;282(15):11521-9. [Content Brief]
[16]. G M Cereghetti, et al. Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15803-8. [Content Brief]
[17]. Philippe A Parone, et al. Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis. Mol Cell Biol. 2006 Oct;26(20):7397-408. [Content Brief]
[18]. Zhigao Wang, et al. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell. 2012 Jan 20;148(1-2):228-43. [Content Brief]
[19]. Sajjan Koirala, et al. Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):E1342-51. [Content Brief]
[20]. Rodolfo Zunino, et al. Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis. J Biol Chem. 2009 Jun 26;284(26):17783-95. [Content Brief]
[21]. Xiaoling Li, et al. The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11. J Biol Chem. 2003 May 9;278(19):17012-20. [Content Brief]
[22]. M Imoto, et al. Identification and functional characterization of a novel human protein highly related to the yeast dynamin-like GTPase Vps1p. J Cell Sci. 1998 May;111 ( Pt 10):1341-9. [Content Brief]
[23]. Chuang-Rung Chang, et al. Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology. J Biol Chem. 2007 Jul 27;282(30):21583-7. [Content Brief]
[24]. Nina A Bonekamp, et al. Dynamin-like protein 1 at the Golgi complex: a novel component of the sorting/targeting machinery en route to the plasma membrane. Exp Cell Res. 2010 Dec 10;316(20):3454-67. [Content Brief]
[25]. Jill A Fahrner, et al. A novel de novo dominant negative mutation in DNM1L impairs mitochondrial fission and presents as childhood epileptic encephalopathy. Am J Med Genet A. 2016 Aug;170(8):2002-11. [Content Brief]
[26]. Ruth Sheffer, et al. Postnatal microcephaly and pain insensitivity due to a de novo heterozygous DNM1L mutation causing impaired mitochondrial fission and function. Am J Med Genet A. 2016 Jun;170(6):1603-7. [Content Brief]
[27]. Catherine S Palmer, et al. Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission. J Biol Chem. 2013 Sep 20;288(38):27584-27593. [Content Brief]
[28]. Claudia Figueroa-Romero, et al. SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. FASEB J. 2009 Nov;23(11):3917-27. [Content Brief]