Histone PARylation factor 1

[1]. Juan José Bonfiglio, et al. Serine ADP-Ribosylation Depends on HPF1. Mol Cell. 2017 Mar 2;65(5):932-940.e6. [Content Brief]

[2]. Luca Palazzo, et al. Serine is the major residue for ADP-ribosylation upon DNA damage. Elife. 2018 Feb 26;7:e34334. [Content Brief]

[3]. Edward Bartlett, et al. Interplay of Histone Marks with Serine ADP-Ribosylation. Cell Rep. 2018 Sep 25;24(13):3488-3502.e5. [Content Brief]

[4]. Silvija Bilokapic, et al. Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Nature. 2020 Sep;585(7826):609-613. [Content Brief]

[5]. Tatyana A Kurgina, et al. Dual function of HPF1 in the modulation of PARP1 and PARP2 activities. Commun Biol. 2021 Nov 3;4(1):1259. [Content Brief]

[6]. Evgeniia Prokhorova, et al. Serine-linked PARP1 auto-modification controls PARP inhibitor response. Nat Commun. 2021 Jul 1;12(1):4055. [Content Brief]

[7]. Jugal Mohapatra, et al. Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling. Elife. 2021 Dec 7;10:e71502. [Content Brief]

[8]. Luka Bacic, et al. Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome. Elife. 2021 Sep 6;10:e71420. [Content Brief]

[9]. Ivo A Hendriks, et al. The regulatory landscape of the human HPF1- and ARH3-dependent ADP-ribosylome. Nat Commun. 2021 Oct 8;12(1):5893. [Content Brief]

[10]. Marcin J Suskiewicz, et al. HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation. Nature. 2020 Mar;579(7800):598-602. [Content Brief]

[11]. Fa-Hui Sun, et al. HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones. Nat Commun. 2021 Feb 15;12(1):1028. [Content Brief]

[12]. Juan José Bonfiglio, et al. An HPF1/PARP1-Based Chemical Biology Strategy for Exploring ADP-Ribosylation. Cell. 2020 Nov 12;183(4):1086-1102.e23. [Content Brief]

[13]. Johannes Rudolph, et al. HPF1 and nucleosomes mediate a dramatic switch in activity of PARP1 from polymerase to hydrolase. Elife. 2021 Mar 8;10:e65773. [Content Brief]

[14]. Deena M Leslie Pedrioli, et al. Comprehensive ADP-ribosylome analysis identifies tyrosine as an ADP-ribose acceptor site. EMBO Rep. 2018 Aug;19(8):e45310. [Content Brief]

[15]. Ian Gibbs-Seymour, et al. HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity. Mol Cell. 2016 May 5;62(3):432-442. [Content Brief]

[16]. Ezeogo Obaji, et al. Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition. Nat Commun. 2021 Jun 9;12(1):3479. [Content Brief]

[17]. Marie-France Langelier, et al. HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications. Nat Commun. 2021 Nov 18;12(1):6675. [Content Brief]