Hyaluronan synthase 2
Definition:
References:
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[1]. K Watanabe, et al. Molecular identification of a putative human hyaluronan synthase. J Biol Chem. 1996 Sep 20;271(38):22945-8. [Content Brief]
[2]. Eugenia Karousou, et al. The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination. J Biol Chem. 2010 Jul 30;285(31):23647-54. [Content Brief]
[3]. Kirsi Rilla, et al. Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3. J Biol Chem. 2013 Feb 22;288(8):5973-83. [Content Brief]
[4]. Kosuke Kasai, et al. Phosphorylation of Thr328 in hyaluronan synthase 2 is essential for hyaluronan synthesis. Biochem Biophys Res Commun. 2020 Dec 17;533(4):732-738. [Content Brief]
[5]. R M Melero-Fernandez de Mera, et al. Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2). Matrix Biol. 2019 Jul;80:85-103. [Content Brief]
[6]. Davide Vigetti, et al. Role of UDP-N-acetylglucosamine (GlcNAc) and O-GlcNAcylation of hyaluronan synthase 2 in the control of chondroitin sulfate and hyaluronan synthesis. J Biol Chem. 2012 Oct 12;287(42):35544-35555. [Content Brief]
[7]. Davide Vigetti, et al. Hyaluronan synthesis is inhibited by adenosine monophosphate-activated protein kinase through the regulation of HAS2 activity in human aortic smooth muscle cells. J Biol Chem. 2011 Mar 11;286(10):7917-7924. [Content Brief]