Islet amyloid polypeptide (IAPP)

Definition:

Islet amyloid polypeptide (IAPP) is a 37-residue polypeptide secreted by the β-cells that acts together with insulin as a regulator of glucose homeostasis.

References:

[1]. Li-Mei Yan, et al. Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2046-51. [Content Brief]

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