Serpin B12
Definition:
Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. May play a role in cell differentiation.
References:
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[1]. Marc D Basson, et al. Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation. Cell Physiol Biochem. 2018;48(3):1274-1290. [Content Brief]
[2]. Y S Askew, et al. SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases. J Biol Chem. 2001 Dec 28;276(52):49320-30. [Content Brief]
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