WD repeat-containing protein 6
Definition:
Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
References:
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[1]. Nicole C McKnight, et al. Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC. EMBO J. 2012 Apr 18;31(8):1931-46. [Content Brief]
[2]. Xiaoduo Xie, et al. Association of LKB1 with a WD-repeat protein WDR6 is implicated in cell growth arrest and p27(Kip1) induction. Mol Cell Biochem. 2007 Jul;301(1-2):115-22. [Content Brief]
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