Boc5 

Boc5 is a non-peptidic glucagon-like peptide-1 receptor agonist. Boc5 causes sustained glycemic control and weight loss in diabetic mice. Boc5 can be used in research of diabetic^[1][2].

Boc5 (0.1-3 mg/mice; i.p.; diabetic db/db mice) has antidiabetic activity and invokes a dose-dependent improvement in glycemic control^[1].
Boc5 (0.1-3 mg/mice; i.p.; diabetic db/db mice) has antiobesity activity and decreases weight in diabetic mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1077.14

C₅₄H₅₂N₄O₁₆S₂

917569-14-3

O=C(C1(NC(C2=CC=C(NC(OC(C)(C)C)=O)C=C2)=O)C(C3=CC=C(OC(C4=CC=CS4)=O)C(OC)=C3)C(C(O)=O)(NC(C5=CC=C(NC(OC(C)(C)C)=O)C=C5)=O)C1C6=CC=C(OC(C7=CC=CS7)=O)C(OC)=C6)O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Su H, et, al. Boc5, a non-peptidic glucagon-like Peptide-1 receptor agonist, invokes sustained glycemic control and weight loss in diabetic mice. PLoS One. 2008 Aug 6;3(8):e2892.  [Content Brief]

  [2]. He M, et, al. A continued saga of Boc5, the first non-peptidic glucagon-like peptide-1 receptor agonist with in vivo activities. Acta Pharmacol Sin. 2012 Feb;33(2):148-54.  [Content Brief]