ODF3 - outer dense fiber of sperm tails 3 Gene

Also Known as CT135; TISP50; SHIPPO1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 113746

About ODF3

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:196,761-200,258 (from NCBI)

This gene has 3 transcripts (splice variants), 192 orthologues and 5 paralogues. Restricted expression toward testis (RPKM 3.9).

Summary

ODF3 is a component of sperm flagella outer dense fibers, which add stiffness, elastic recoil, and protection against shearing forces during sperm movement.[supplied by OMIM, Apr 2004]

ODF3 Products (2)

mRNA Protein Name
NM_001286136.2 NP_001273065.1 outer dense fiber protein 3 isoform 2
NM_053280.5 NP_444510.2 outer dense fiber protein 3 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23355646 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ODF3 Protein Structure

SHIPPO-rpt

SHIPPO-rpt: Sperm-tail PG-rich repeat (26 - 57)

SHIPPO-rpt

SHIPPO-rpt: Sperm-tail PG-rich repeat (66 - 94)

SHIPPO-rpt

SHIPPO-rpt: Sperm-tail PG-rich repeat (100 - 130)

SHIPPO-rpt

SHIPPO-rpt: Sperm-tail PG-rich repeat (136 - 168)

SHIPPO-rpt

SHIPPO-rpt: Sperm-tail PG-rich repeat (179 - 207)

SHIPPO-rpt

SHIPPO-rpt: Sperm-tail PG-rich repeat (216 - 244)

  • 0
  • 100
  • 200
  • 254 a.a.
Protein Preferred Names Protein Names

outer dense fiber protein 3

  • cancer/testis antigen 135

ODF3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CIMAP1A Q96PU9 DYNLL1 Homo sapiens P63167
Y2H Prey Pooling
32296183
Intra
CIMAP1A Q96PU9 DYNLL1 Homo sapiens P63167
Y2H Array
32296183
Intra
CIMAP1A Q96PU9 HOGA1 Homo sapiens Q86XE5
Y2H Prey Pooling
32296183
Intra
CIMAP1A Q96PU9 HOGA1 Homo sapiens Q86XE5
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Salpingitis
Chronic Salpingitis
Pyosalpinx

  • Pyosalpingitis
Lymphogranuloma Venereum

  • Climatic Or Tropical Bubo

  • Durand-Nicolas-Favre Disease

  • Lymphogranuloma Inguinale

  • Poradenitis Inguinale

  • Strumous Bubo

  • Lgv
Granuloma Inguinale

  • Donovanosis

  • Pudendal Ulcer

  • Granuloma Inguinale Tropicum

  • Granuloma Pudendi Tropicum
Primary Ciliary Dyskinesia

  • Immotile Cilia Syndrome

  • Kartagener Syndrome

  • Dextrocardia Bronchiectasis And Sinusitis

  • Pcd

  • Ciliary Motility Disorders

  • Ciliary Motility Disorder

  • Immotile Ciliary Syndrome

  • Ciliary Dyskinesia Primary

  • Ics

  • Polynesian Bronchiectasis

  • Dextrocardia-Bronchiectasis-Sinusitis Syndrome

  • Immotile Cilia Syndrome, Kartagener Type

  • Primary Ciliary Dyskinesia And Situs Inversus

  • Primary Ciliary Dyskinesia, Kartagener Type

  • Siewert Syndrome

  • Dyskinesia, Ciliary, Primary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09753 ODF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ODF3 VGNC VGNC:44101
Bos taurus ODF3 VGNC VGNC:32403
Macaca mulatta ODF3 VGNC VGNC:75438
Rattus norvegicus ODF3 RGD RGD:1310028
Felis catus ODF3 VGNC VGNC:63950
Mus musculus ODF3 MGD MGI:1916537
Others ODF3 NCBI