TAMALIN - trafficking regulator and scaffold protein tamalin Gene
Also Known as GRASP
Species: Homo sapiens
About TAMALIN
This gene has 8 transcripts (splice variants), 185 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 8.3), fat (RPKM 7.8) and 23 other tissues.
Summary
This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 Metabotropic Glutamate Receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012]
TAMALIN Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001271856.2 | NP_001258785.1 | protein TAMALIN isoform 2 |
| NM_181711.4 | NP_859062.1 | protein TAMALIN isoform 1 |
TAMALIN Protein Structure
PDZ: PDZ domain (Also known as DHR or GLGF) (102 - 185)
- 0
- 100
- 200
- 300
- 395 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
protein TAMALIN |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Schizophrenia 6 |
|
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | TAMALIN | RGD | RGD:70554 |
| Macaca mulatta | TAMALIN | VGNC | VGNC:72966 |
| Mus musculus | TAMALIN | MGD | MGI:1860303 |
| Bos taurus | TAMALIN | VGNC | VGNC:29628 |
| Others | TAMALIN | NCBI |