RPL22L1 - ribosomal protein L22 like 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 200916

About RPL22L1

This gene has 6 transcripts (splice variants), 270 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 15.2), appendix (RPKM 13.6) and 25 other tissues.

Summary

Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Predicted to be located in ribosome. [provided by Alliance of Genome Resources, Apr 2022]

RPL22L1 Products (2)

mRNA Protein Name
NM_001099645.2 NP_001093115.1 60S ribosomal protein L22-like 1 isoform 1
NM_001320451.2 NP_001307380.1 60S ribosomal protein L22-like 1 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPL22L1 Protein Structure

Ribosomal_L22e

Ribosomal_L22e: Ribosomal L22e protein family (10 - 119)

  • 0
  • 100
  • 122 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L22-like 1

  • large ribosomal subunit protein eL22-like 1

RPL22L1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RPL22L1 Q6P5R6 SDCBP2 Homo sapiens Q9H190
Validated Y2H
32296183
Intra
RPL22L1 Q6P5R6 SDCBP2 Homo sapiens Q9H190
Y2H Prey Pooling
32296183
Intra
RPL22L1 Q6P5R6 SDCBP2 Homo sapiens Q9H190
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Colon Sarcoma

  • Colonic Sarcoma
Diamond-Blackfan Anemia

  • Congenital Pure Red Cell Aplasia

  • Aase Syndrome

  • Erythrogenesis Imperfecta

  • Anemia, Diamond-Blackfan

  • Congenital Hypoplastic Anemia

  • Aase-Smith Ii Syndrome

  • Bds

  • Blackfan-Diamond Anemia

  • Congenital Prca

  • Congenital Hypoplastic Anemia, Blackfan-Diamond Type

  • Dba

  • Blackfan - Diamond Syndrome

  • Chronic Constitutional Pure Red Cell Anaemia

  • Anemia Diamond Blackfan Type

  • Anemia Congenital Erythroid Hypoplastic

  • Aregenerative Anemia Chronic Congenital

  • Blackfan Diamond Syndrome

  • Red Cell Aplasia, Pure Hereditary

  • Aase-Smith Syndrome Ii

  • Bda

  • Blackfan Diamond Anemia

  • Blackfan-Diamond Disease

  • Blackfan-Diamond Syndrome

  • Chronic Congenital Agenerative Anemia

  • Congenital Erythroid Hypoplastic Anemia

  • Congenital Hypoplastic Anemia Of Blackfan And Diamond

  • Congenital Pure Red Cell Anemia

  • Hypoplastic Congenital Anemia

  • Inherited Erythroblastopenia

  • Pure Hereditary Red Cell Aplasia

  • Anemia, Hypoplastic, Congenital

  • Anemia Hypoplastic Congenital

  • Fanconi Anemia

  • Constitutional Aplastic Anemia

  • Diamond-Blackfan Anemia 1

  • Aase Smith Syndrome 2

  • Congenital Red Cell Aplasia

  • Red Cell Aplasia Of Infants

  • Pure Red Cell Aplasia Of Infants

  • Congenital Red Cell Aplastic Anaemia

  • Congenital Pure Red Cell Anaemia

  • Congenital Erythroid Hypoplasia

  • Pearson Marrow-Pancreas Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12174 RPL22L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RPL22L1 MGD MGI:1915278
Rattus norvegicus RPL22L1 RGD RGD:1309517
Canis familiaris RPL22L1 VGNC VGNC:45716
Felis catus RPL22L1 VGNC VGNC:102832
Macaca mulatta RPL22L1 VGNC VGNC:84091
Others RPL22L1 NCBI