FOXJ3 - forkhead box J3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 22887

About FOXJ3

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:42,176,548-42,335,880 (from NCBI)

This gene has 9 transcripts (splice variants), 161 orthologues and 42 paralogues. Ubiquitous expression in thyroid (RPKM 10.6), testis (RPKM 10.1) and 25 other tissues.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FOXJ3 Products (4)

mRNA Protein Name
NM_001198850.2 NP_001185779.1 forkhead box protein J3 isoform 1
NM_001198851.2 NP_001185780.1 forkhead box protein J3 isoform 1
NM_001198852.2 NP_001185781.1 forkhead box protein J3 isoform 2
NM_014947.5 NP_055762.3 forkhead box protein J3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
22740631 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
23332764 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
22740631 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FOXJ3 Protein Structure

Forkhead

Forkhead: Forkhead domain (78 - 162)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 622 a.a.
Protein Preferred Names Protein Names

forkhead box protein J3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05058 FOXJ3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta FOXJ3 VGNC VGNC:72596
Bos taurus FOXJ3 VGNC VGNC:29091
Rattus norvegicus FOXJ3 RGD RGD:1311770
Felis catus FOXJ3 VGNC VGNC:62338
Mus musculus FOXJ3 MGD MGI:2443432
Canis familiaris FOXJ3 VGNC VGNC:40956
Others FOXJ3 NCBI