GPR26 - G protein-coupled receptor 26 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2849

About GPR26

Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): 10:123,666,355-123,697,399 (from NCBI)

This gene has 1 transcript (splice variant), 248 orthologues and 3 paralogues. Restricted expression toward brain (RPKM 2.1).

Summary

This gene encodes a G protein-couple receptor protein. G-protein-coupled receptors are a large family of membrane proteins that are involved in cellular responses to environmental stimuli, neurotransmitters, and Hormones. The encoded protein may play a role in neurodegenerative diseases. Epigenetic silencing of this gene has been observed in gliomas. [provided by RefSeq, Sep 2016]

GPR26 Products (1)

mRNA Protein Name
NM_153442.4 NP_703143.1 G-protein coupled receptor 26

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables G protein-coupled receptor activity IDA
IDA: Inferred from direct assay
17363172 GOA
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
17363172 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR26 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (23 - 294)

  • 0
  • 100
  • 200
  • 300
  • 337 a.a.
Protein Preferred Names Protein Names

G-protein coupled receptor 26

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05698 GPR26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20033 Gpr26 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26536 Gpr26 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus GPR26 VGNC VGNC:55954
Mus musculus GPR26 MGD MGI:2441758
Canis familiaris GPR26 VGNC VGNC:41428
Macaca mulatta GPR26 VGNC VGNC:106054
Rattus norvegicus GPR26 RGD RGD:619843
Others GPR26 NCBI