Atxn2 - ataxin 2 Gene
Also Known as Sca2
Species: Rattus norvegicus
Summary
Predicted to enable RNA binding activity; epidermal growth factor receptor binding activity; and protein C-terminus binding activity. Predicted to be involved in P-body assembly; negative regulation of receptor internalization; and stress granule assembly. Predicted to act upstream of or within several processes, including homeostasis of number of cells; neuromuscular process; and neuron differentiation. Predicted to be located in cytosol; perinuclear region of cytoplasm; and trans-Golgi network. Predicted to be part of polysome. Predicted to be active in cytoplasmic stress granule. Human ortholog(s) of this gene implicated in late onset Parkinson's disease and spinocerebellar ataxia type 2. Orthologous to human ATXN2 (ataxin 2). [provided by Alliance of Genome Resources, Apr 2022]
Atxn2 Products (32)
| mRNA | Protein | Name |
|---|---|---|
| XM_039090155.1 | XP_038946083.1 | ataxin-2 isoform X14 |
| XM_039090143.1 | XP_038946071.1 | ataxin-2 isoform X3 |
| XM_039090150.1 | XP_038946078.1 | ataxin-2 isoform X9 |
| XM_039090152.1 | XP_038946080.1 | ataxin-2 isoform X11 |
| XM_039090147.1 | XP_038946075.1 | ataxin-2 isoform X6 |
| XM_039090142.1 | XP_038946070.1 | ataxin-2 isoform X2 |
| XM_039090151.1 | XP_038946079.1 | ataxin-2 isoform X10 |
| XM_039090146.1 | XP_038946074.1 | ataxin-2 isoform X5 |
| XM_039090154.1 | XP_038946082.1 | ataxin-2 isoform X13 |
| XM_039090148.1 | XP_038946076.1 | ataxin-2 isoform X7 |
| XM_039090141.1 | XP_038946069.1 | ataxin-2 isoform X1 |
| XM_039090144.1 | XP_038946072.1 | ataxin-2 isoform X4 |
| XM_039090149.1 | XP_038946077.1 | ataxin-2 isoform X8 |
| XM_039090153.1 | XP_038946081.1 | ataxin-2 isoform X12 |
| XM_039090158.1 | XP_038946086.1 | ataxin-2 isoform X16 |
| XM_039090157.1 | XP_038946085.1 | ataxin-2 isoform X15 |
| XM_039090155.1 | XP_038946083.1 | ataxin-2 isoform X14 |
| XM_039090143.1 | XP_038946071.1 | ataxin-2 isoform X3 |
| XM_039090150.1 | XP_038946078.1 | ataxin-2 isoform X9 |
| XM_039090152.1 | XP_038946080.1 | ataxin-2 isoform X11 |
| XM_039090147.1 | XP_038946075.1 | ataxin-2 isoform X6 |
| XM_039090142.1 | XP_038946070.1 | ataxin-2 isoform X2 |
| XM_039090151.1 | XP_038946079.1 | ataxin-2 isoform X10 |
| XM_039090146.1 | XP_038946074.1 | ataxin-2 isoform X5 |
| XM_039090154.1 | XP_038946082.1 | ataxin-2 isoform X13 |
| XM_039090148.1 | XP_038946076.1 | ataxin-2 isoform X7 |
| XM_039090141.1 | XP_038946069.1 | ataxin-2 isoform X1 |
| XM_039090144.1 | XP_038946072.1 | ataxin-2 isoform X4 |
| XM_039090149.1 | XP_038946077.1 | ataxin-2 isoform X8 |
| XM_039090153.1 | XP_038946081.1 | ataxin-2 isoform X12 |
| XM_039090158.1 | XP_038946086.1 | ataxin-2 isoform X16 |
| XM_039090157.1 | XP_038946085.1 | ataxin-2 isoform X15 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ataxin-2 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-402873 | DMTr-2'-O-C16-rC(Ac)-3'-CE-phosphoramidite | Inhibitor | / | Unkown |
| HY-RS01256 | ATXN2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS01257 | ATXN2L Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-180474 | LP293-p | / | Unkown | |
| HY-RS21491 | Atxn2 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS21824 | Atxn2l Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28009 | Atxn2 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS28341 | Atxn2l Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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