EQTN - equatorin Gene

Also Known as AFAF; SPACA8; C9orf11

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54586

About EQTN

Cytogenetic location: 9p21.2 Genomic coordinates (GRCh38): 9:27,284,654-27,297,150 (from NCBI)

This gene has 4 transcripts (splice variants) and 62 orthologues. Restricted expression toward testis (RPKM 7.3).

Summary

Predicted to be involved in acrosomal vesicle exocytosis; endocytosis; and fusion of sperm to egg plasma membrane involved in single fertilization. Predicted to be located in acrosomal membrane; early endosome; and nucleus. Predicted to be active in inner acrosomal membrane; outer acrosomal membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EQTN Products (2)

mRNA Protein Name
NM_001161585.2 NP_001155057.1 equatorin isoform 2 precursor
NM_020641.3 NP_065692.2 equatorin isoform 1 precursor

EQTN Protein Structure

Afaf

Afaf: Acrosome formation-associated factor (53 - 250)

  • 0
  • 100
  • 200
  • 294 a.a.
Protein Preferred Names Protein Names

equatorin

  • Acrosome formation associated factor

Related Diseases

Diseases Alias
Bronchiectasis 1
Tumoral Calcinosis, Hyperphosphatemic, Familial, 1

  • Hyperphosphatemic Familial Tumoral Calcinosis

  • Hftc

  • Hyperostosis-Hyperphosphatemia Syndrome

  • Familial Hyperphosphatemic Tumoral Calcinosis/Hyperphosphatemic Hyperostosis Syndrome

  • Tumoral Calcinosis, Hyperphosphatemic, Familial

  • Phptc

  • Lipocalcinogranulomatosis

  • Morbus Teutschlaender

  • Hhs

  • Hyperostosis With Hyperphosphatemia

  • Cortical Hyperostosis With Hyperphosphatemia

  • Primary Hyperphosphatemic Tumoral Calcinosis

  • Familial Tumoral Calcinosis

  • HFTC1

  • Hypercalcemic Tumoral Calcinosis

  • Hyperphosphatemia Hyperostosis

  • Hyperphosphatemia Hyperostosis Syndrome

  • Hyperphosphatemia Tumoral Calcinosis

  • Tumoral Calcinosis

  • Calcinosis, Tumoral, With Hyperphosphatemia

  • Tumoral Calcinosis, Primary Hyperphosphatemic

  • Teutschlaender Disease, Familial

  • Familial Teutschlaender Disease

  • Tumoral Calcinosis With Hyperphosphatemia

  • Familial Tumoral Calcinosis/Hyperostosis-Hyperphosphatemia Syndrome

  • Ftc/Hhs

  • Familial Tumoral Calcinosis With Hyperphosphatemia

  • Teutschlaender Disease

  • Tumoral Calcinosis Primary Hyperphosphatemic

  • Calcinosis, Tumoral, Hyperphosphatemic, Familial
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04461 EQTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29489 Eqtn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus EQTN VGNC VGNC:102923
Mus musculus EQTN MGD MGI:1915003
Bos taurus EQTN VGNC VGNC:56963
Canis familiaris EQTN VGNC VGNC:51714
Macaca mulatta EQTN VGNC VGNC:72040
Rattus norvegicus EQTN RGD RGD:1563332
Others EQTN NCBI