Bcan - brevican Gene

Also Known as Cspg7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12032

Summary

Predicted to enable calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Involved in synapse maturation. Acts upstream of or within hippocampus development. Located in extracellular matrix and glutamatergic synapse. Is expressed in several structures, including brain; genitourinary system; sensory organ; skeleton; and spinal cord. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human BCAN (brevican). [provided by Alliance of Genome Resources, Apr 2022]

Bcan Products (18)

mRNA Protein Name
NM_001109758.2 NP_001103228.1 brevican core protein isoform 2 precursor
NM_001409541.1 NP_001396470.1 brevican core protein isoform 1 precursor
NM_001409542.1 NP_001396471.1 brevican core protein isoform 1 precursor
NM_001409543.1 NP_001396472.1 brevican core protein isoform 1 precursor
NM_001409545.1 NP_001396474.1 brevican core protein isoform 1 precursor
NM_001409546.1 NP_001396475.1 brevican core protein isoform 3 precursor
NM_001409547.1 NP_001396476.1 brevican core protein isoform 4 precursor
NM_001409548.1 NP_001396477.1 brevican core protein isoform 4 precursor
NM_001409549.1 NP_001396478.1 brevican core protein isoform 5 precursor
NM_001409550.1 NP_001396479.1 brevican core protein isoform 5 precursor
NM_001409551.1 NP_001396480.1 brevican core protein isoform 6 precursor
NM_001409552.1 NP_001396481.1 brevican core protein isoform 7
NM_001409553.1 NP_001396482.1 brevican core protein isoform 8 precursor
NM_001409554.1 NP_001396483.1 brevican core protein isoform 2 precursor
NM_001409555.1 NP_001396484.1 brevican core protein isoform 2 precursor
NM_001409556.1 NP_001396485.1 brevican core protein isoform 2 precursor
NM_001409557.1 NP_001396486.1 brevican core protein isoform 9 precursor
NM_007529.3 NP_031555.2 brevican core protein isoform 1 precursor
Biological Process GO Annotation Evidence Références Source
acts upstream of or within hippocampus development IMP
IMP: Inferred from mutant phenotype
12370289 MGI
involved in synapse maturation IDA
IDA: Inferred from direct assay
28712654 MGI
involved in synapse maturation IEP
IEP: Inferred from expression pattern
28712654 MGI
involved in synapse maturation IMP
IMP: Inferred from mutant phenotype
28712654 MGI
Cellular Component GO Annotation Evidence Références Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
19141078 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28712654 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
28712654 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28712654 MGI
located in perineuronal net IDA
IDA: Inferred from direct assay
14550776 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

brevican core protein

Orthologs Information

Species Symbol Source ID
Homo sapiens Bcan NCBI NCBI:63827