Myt1l - myelin transcription factor 1-like Gene

Also Known as Nztf1; Pmng1; Png-1; mKIAA1106; 2900046C06Rik; 2900093J19Rik; C630034G21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17933

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II; neuron development; and neuron fate specification. Located in nucleus. Is expressed in several structures, including eye; genitourinary system; nervous system; and olfactory epithelium. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Myt1l Products (10)

mRNA Protein Name
NM_001093775.1 NP_001087244.1 myelin transcription factor 1-like protein isoform 1
NM_001093776.1 NP_001087245.1 myelin transcription factor 1-like protein isoform 2
NM_001093778.1 NP_001087247.1 myelin transcription factor 1-like protein isoform 3
NM_001361655.1 NP_001348584.1 myelin transcription factor 1-like protein isoform 4
NM_001361656.1 NP_001348585.1 myelin transcription factor 1-like protein isoform 2
NM_001361657.1 NP_001348586.1 myelin transcription factor 1-like protein isoform 2
NM_001361658.1 NP_001348587.1 myelin transcription factor 1-like protein isoform 5
NM_001361659.1 NP_001348588.1 myelin transcription factor 1-like protein isoform 6
NM_001361660.1 NP_001348589.1 myelin transcription factor 1-like protein isoform 7
NM_008666.3 NP_032692.2 myelin transcription factor 1-like protein isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
24243019 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
28379941 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15935060 MGI
Biological Process GO Annotation Evidence Références Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
28379941 MGI
involved in nervous system development IDA
IDA: Inferred from direct assay
24243019 MGI
involved in neuron development IDA
IDA: Inferred from direct assay
24243019 MGI
involved in neuron differentiation IDA
IDA: Inferred from direct assay
24243019 MGI
involved in neuron fate commitment IDA
IDA: Inferred from direct assay
24243019 MGI
involved in neuron fate specification IDA
IDA: Inferred from direct assay
24243019 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
24243019 MGI
Cellular Component GO Annotation Evidence Références Source
located in nucleus IDA
IDA: Inferred from direct assay
9373037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myelin transcription factor 1-like protein

  • NZF-1

  • myT1-L

  • neural zinc finger factor 1

  • neural zinc finger protein NZF-1

  • neural zinc finger transcription factor 1

  • postmeiotic neural gene 1

  • postmitotic neural gene 1 protein

  • zinc finger protein Png-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS08974 MYT1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21661 Myt1l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28179 Myt1l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myt1l NCBI NCBI:23040