Sycp3 - synaptonemal complex protein 3 Gene

Also Known as Cor1; Scp3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20962

Summary

Predicted to enable DNA binding activity. Involved in meiotic chromosome segregation and spermatogenesis. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; meiosis I cell cycle process; and sperm chromatin condensation. Located in condensed chromosome and male germ cell nucleus. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and primordial germ cell. Used to study azoospermia. Human ortholog(s) of this gene implicated in spermatogenic failure 4. Orthologous to human SYCP3 (synaptonemal complex protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Sycp3 Products (1)

mRNA Protein Name
NM_011517.2 NP_035647.2 synaptonemal complex protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
12759374 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
involved in chiasma assembly IDA
IDA: Inferred from direct assay
12004129 MGI
acts upstream of or within chiasma assembly IGI
IGI: Inferred from genetic interaction
22164254 MGI
involved in female meiosis chromosome segregation IDA
IDA: Inferred from direct assay
12004129 MGI
involved in female meiosis sister chromatid cohesion IDA
IDA: Inferred from direct assay
15870106 MGI
acts upstream of or within homologous chromosome pairing at meiosis IMP
IMP: Inferred from mutant phenotype
15870106 MGI
acts upstream of or within lateral element assembly IGI
IGI: Inferred from genetic interaction
22164254 MGI
acts upstream of or within meiotic DNA repair synthesis IGI
IGI: Inferred from genetic interaction
22164254 MGI
acts upstream of or within meiotic cell cycle IDA
IDA: Inferred from direct assay
12091911 MGI
acts upstream of or within mitotic cell cycle IDA
IDA: Inferred from direct assay
10809667 MGI
acts upstream of or within sperm DNA condensation IGI
IGI: Inferred from genetic interaction
22164254 MGI
acts upstream of or within spermatogenesis IGI
IGI: Inferred from genetic interaction
22164254 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
10678170 MGI
involved in synaptonemal complex assembly IDA
IDA: Inferred from direct assay
10678170 MGI
acts upstream of or within synaptonemal complex assembly IGI
IGI: Inferred from genetic interaction
22164254 MGI
Cellular Component GO Annotation Evidence Références Source
located in chromosome IDA
IDA: Inferred from direct assay
10794082 MGI
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
28380054 MGI
located in condensed chromosome IDA
IDA: Inferred from direct assay
10809667 MGI
located in condensed chromosome, centromeric region IDA
IDA: Inferred from direct assay
22854038 MGI
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
18316482 MGI
located in female germ cell nucleus IDA
IDA: Inferred from direct assay
21621532 MGI
located in lateral element IDA
IDA: Inferred from direct assay
10678170 MGI
located in male germ cell nucleus IDA
IDA: Inferred from direct assay
17696610 MGI
located in synaptonemal complex IDA
IDA: Inferred from direct assay
12815066 MGI
located in transverse filament IDA
IDA: Inferred from direct assay
15870106 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptonemal complex protein 3

  • SCP-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14072 SYCP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21776 Sycp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28293 Sycp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sycp3 NCBI NCBI:50511