SLC39A12 - solute carrier family 39 member 12 Gene

Also Known as ZIP12; ZIP-12; LZT-Hs8; bA570F3.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 221074

About SLC39A12

Cytogenetic location: 10p12.33 Genomic coordinates (GRCh38): 10:17,951,918-18,043,285 (from NCBI)

This gene has 4 transcripts (splice variants), 189 orthologues and 6 paralogues. Restricted expression toward brain (RPKM 9.2).

Summary

Zinc is an essential cofactor for hundreds of Enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008]

SLC39A12 Products (4)

mRNA Protein Name
NM_001145195.2 NP_001138667.1 zinc transporter ZIP12 isoform 1 precursor
NM_001282733.2 NP_001269662.1 zinc transporter ZIP12 isoform 3 precursor
NM_001282734.2 NP_001269663.1 zinc transporter ZIP12 isoform 4
NM_152725.4 NP_689938.2 zinc transporter ZIP12 isoform 2 precursor

SLC39A12 Protein Structure

Zip

Zip: ZIP Zinc transporter (369 - 683)

  • 0
  • 200
  • 400
  • 600
  • 691 a.a.
Protein Preferred Names Protein Names

zinc transporter ZIP12

  • LIV-1 subfamily of ZIP zinc transporter 8

Related Diseases

Diseases Alias
Acrodermatitis Enteropathica, Zinc-Deficiency Type

  • Acrodermatitis Enteropathica

  • AEZ

  • Enteropathica

  • Brandt Syndrome

  • Ae

  • Acrodermatitis Enteropathica Zinc Deficiency Type

  • Danbolt-Cross Syndrome

  • Acrodermatitis Enteropathica, Zinc Deficiency Type

  • Inherited Zinc Deficiency

  • Acrodermatitis Enteropathica, Zinc Deficiency

  • Danbolt-Closs Syndrome

  • Primary Zinc Malabsorption Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS13231 SLC39A12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SLC39A12 MGD MGI:2139274
Felis catus SLC39A12 VGNC VGNC:65356
Canis familiaris SLC39A12 VGNC VGNC:46401
Rattus norvegicus SLC39A12 RGD RGD:1309305
Bos taurus SLC39A12 VGNC VGNC:34860
Macaca mulatta SLC39A12 VGNC VGNC:77539
Others SLC39A12 NCBI