Nampt-IN-7
Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM.
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- CAS No.: 1223378-42-4
- Formule: C20H21N5O3
- Masse moléculaire:379.41
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
IC50: 7.31 ± 1.59 μM (NAMPT)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
24.28 μM
Compound: GF8
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay
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[PMID: 31818629] |
Chemical Information
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CAS No. 1223378-42-4
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Masse moléculaire 379.41
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Formule C20H21N5O3
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SMILES
CCOC(C1=CC=C(C=C1)NC(NCC2=CC(N3C=CN=C3C)=NC=C2)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nampt-IN-7 Related Classifications
HY-147756 Related Classifications
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