1223378-42-4
1223378-42-4
Chemical Structure
Nampt-IN-7
- CAS No.: 1223378-42-4
- Formula:C20H21N5O3
- Molecular Weight:379.41
IUPAC Name: ethyl 4-(3-((2-(2-methyl-1H-imidazol-1-yl)pyridin-4-yl)methyl)ureido)benzoate
InChIKey: REJWICBGFGQVML-UHFFFAOYSA-N
SMILES: CCOC(C1=CC=C(C=C1)NC(NCC2=CC(N3C=CN=C3C)=NC=C2)=O)=O
Biological Activity: Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM[1].
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Nampt-IN-7 | Nampt-IN-7 (compound GF8) is a potent NAMPT inhibitor, with an IC50 of 7.31 μM. Nampt-IN-7 also displays cytotoxic activity against human HepG2 hepatocellular carcinoma cell line with an IC50 of 24.28 μM. | |||||||||||||||||||||
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References
Keywords
