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RasGRP3 ligand 1

RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a K_i of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research.

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CAS No.: 2229068-13-5
Formule: C₂₁H₂₅NO₅
Masse moléculaire:371.43

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

RasGRP3 ligand 1 Chemical Structure

CAS No.: 2229068-13-5

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
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Activité biologique

Description

RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a K_i of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research^[1].

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In Vitro

RasGRP3 ligand 1 (1-10000 nM, 30 min) activates Ras in a dose dependent manner in RasGRP over expressing HEK293, LNCaP and Ramos cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2229068-13-5
Masse moléculaire 371.43
Formule C₂₁H₂₅NO₅
SMILES

CN1C2=CC=CC=C2C(/C=C3CC(CO)(OC\3=O)COC(C(C)(C)C)=O)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ann J, et al. α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands. J Med Chem. 2018 Jul 26;61(14):6261-6276. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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