100276-03-7
Chemical Structure
BAY R3401
- CAS No.: 100276-03-7
- Formula:C20H22ClNO4
- Molecular Weight:375.85
IUPAC Name: isopropyl 4-(2-chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylate
InChIKey: NPUSXSOBPNHOPH-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N(CC)C(COC2=O)=C2C1C3=CC=CC=C3Cl)OC(C)C
Biological Activity: BAY R3401 is an orally active glycogen phosphorylase inhibitor that can achieve irreversible and non-selective inhibition of hepatic glycogenolysis. BAY R3401 inhibits glycogenolysis in liver cells, with IC50 values of 27.06 and 52.83 μM in HL-7702 and HepG2 cells, respectively. BAY R3401 can be used for the research of type 2 diabetes[1].
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BAY R3401 | BAY R3401 is an orally active glycogen phosphorylase inhibitor that can achieve irreversible and non-selective inhibition of hepatic glycogenolysis. BAY R3401 inhibits glycogenolysis in liver cells, with IC50 values of 27.06 and 52.83 μM in HL-7702 and HepG2 cells, respectively. BAY R3401 can be used for the research of type 2 diabetes. | |||||||||||||||||||||
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Keywords
