10212-31-4
10212-31-4
Chemical Structure
2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone
- CAS No.: 10212-31-4
- Formula:C10H15N3O5
- Molecular Weight:257.24
IUPAC Name: 2-amino-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-4(1H)-one
InChIKey: JUFWRFOUTDSMSO-JAGXHNFQSA-N
SMILES: O[C@H]1[C@H](O)[C@H](N2C(N)=NC(C(C)=C2)=O)O[C@@H]1CO
Biological Activity: 2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone | 2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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