1072833-77-2
1072833-77-2
Chemical Structure
Ixazomib
Synonym(s): MLN2238
- CAS No.: 1072833-77-2
- Formula:C14H19BCl2N2O4
- Molecular Weight:361.03
IUPAC Name: (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid
InChIKey: MXAYKZJJDUDWDS-LBPRGKRZSA-N
SMILES: OB([C@@H](NC(CNC(C1=CC(Cl)=CC=C1Cl)=O)=O)CC(C)C)O
Biological Activity: Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ixazomib | 99.30% | Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | ||||||||||||||||||||
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Ixazomib (Standard) | ≥98% | Ixazomib (Standard) is the analytical standard of Ixazomib. This product is intended for research and analytical applications. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | ||||||||||||||||||||
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Ixazomib-13C2,15N | Ixazomib-13C2,15N is 13C and 15N labeled Ixazomib. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | |||||||||||||||||||||
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Ixazomib-d7 | Ixazomib-d7 is the deuterium labeled Ixazomib (HY-10453). Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | |||||||||||||||||||||
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