1072833-77-2
Chemical Structure
Ixazomib
Synonym(s): MLN2238
- CAS No.: 1072833-77-2
- Formula:C14H19BCl2N2O4
- Molecular Weight:361.03
IUPAC Name: (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid
InChIKey: MXAYKZJJDUDWDS-LBPRGKRZSA-N
SMILES: OB([C@@H](NC(CNC(C1=CC(Cl)=CC=C1Cl)=O)=O)CC(C)C)O
Biological Activity: Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).
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Ixazomib | 99.30% | Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | ||||||||||||||||||||
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Ixazomib (Standard) | ≥98% | Ixazomib (Standard) is the analytical standard of Ixazomib. This product is intended for research and analytical applications. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | ||||||||||||||||||||
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Ixazomib-13C2,15N | Ixazomib-13C2,15N is 13C and 15N labeled Ixazomib. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | |||||||||||||||||||||
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Ixazomib-d7 | Ixazomib-d7 is the deuterium labeled Ixazomib (HY-10453). Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | |||||||||||||||||||||
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Similarity Score 0.61
HY-175597ClpP modulator-1 -
Similarity Score 0.60
HY-15827NSC 405020 -
Similarity Score 0.59
HY-19838JNJ-63533054 -
Similarity Score 0.59
HY-4017215-CNAC -
Similarity Score 0.58
HY-153688SORT-PGRN interaction inhibitor 3 -
Similarity Score 0.57
HY-184573Dopamine D2 receptor modulator-1 -
Similarity Score 0.57
HY-10452RIxazomib citrate (Standard) -
Similarity Score 0.57
HY-W142019Benzoyl-DL-leucine -
Similarity Score 0.57
HY-W142035N-Benzoyl-L-leucine -
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