1 Result for "

114899-77-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "114899-77-3" in MCE Product Catalog:

Cat. No.: HY-50936S
Synonyms: Ecteinascidin 743-d3; ET-743-d3
Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment .