1188910-76-0
1188910-76-0
Chemical Structure
Agerafenib
Synonym(s): CEP-32496; RXDX-105
- CAS No.: 1188910-76-0
- Formula:C24H22F3N5O5
- Molecular Weight:517.46
IUPAC Name: 1-(3-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea
InChIKey: DKNUPRMJNUQNHR-UHFFFAOYSA-N
SMILES: O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)NC2=CC=CC(OC3=C(C=C(OC)C(OC)=C4)C4=NC=N3)=C2
Biological Activity: Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Agerafenib | 99.78% | Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM. | ||||||||||||||||||||
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