1188910-76-0

Agerafenib Chemical Structure
1188910-76-0

Chemical Structure

Agerafenib

Synonym(s): CEP-32496; RXDX-105

  • CAS No.: 1188910-76-0
  • Formula:C24H22F3N5O5
  • Molecular Weight:517.46

IUPAC Name: 1-(3-((6,7-dimethoxyquinazolin-4-yl)oxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea

InChIKey: DKNUPRMJNUQNHR-UHFFFAOYSA-N

SMILES: O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)NC2=CC=CC(OC3=C(C=C(OC)C(OC)=C4)C4=NC=N3)=C2

Biological Activity: Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM.

Cat. No. Product Name Purity Description Pricing
HY-15200 		Agerafenib 99.78% Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

Keywords