1201658-81-2
Chemical Structure
Anserine-d4
- CAS No.: 1201658-81-2
- Formula:C10H12D4N4O3
- Molecular Weight:244.28
IUPAC Name: Na-(3-aminopropanoyl-2,2,3,3-d4)-Np-methyl-L-histidine
InChIKey: MYYIAHXIVFADCU-XDTSEJTKSA-N
SMILES: O=C(O)[C@H](CC1=CN=CN1C)NC(C([2H])([2H])C([2H])([2H])N)=O
Biological Activity: Anserine-d4 is the deuterium labeled Anserine. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Anserine-d4 | 99.38% | Anserine-d4 is the deuterium labeled Anserine. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice. | ||||||||||||||||||||
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Anserine (Standard) | ≥98% | Anserine (Standard) is the analytical standard of Anserine. This product is intended for research and analytical applications. Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice. | ||||||||||||||||||||
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Anserine-d4 hydrochloride | Anserine-d4 hydrochloride is the deuterium labeled Anserine (HY-113354). Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice. | |||||||||||||||||||||
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Anserine | 99.85% | Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine has blood-brain barrier permeability, and improves memory functions in Alzheimer's disease (AD)-model mice. | ||||||||||||||||||||
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Similarity Score 0.91
HY-W011393L-Anserine nitrate -
Similarity Score 0.81
HY-N19860L-Balenine -
Similarity Score 0.79
HY-W013494RL-Carnosine (Standard) -
Similarity Score 0.79
HY-W013494SL-Carnosine-d4 -
Similarity Score 0.73
HY-114883Homocarnosine -
Similarity Score 0.69
HY-133026RN-Acetylcarnosine (Standard) -
Similarity Score 0.69
HY-W514708H-Ala-Gis-OH -
Similarity Score 0.68
HY-P5097γ-Glu-His -
Similarity Score 0.67
HY-P4288Beta-Asp-His -
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Boldyrev AA, et al. The histidine-containing dipeptides, carnosine and anserine: distribution, properties and biological significance. Adv Enzyme Regul. 1990;30:175-94. [Content Brief]
