1415637-72-7
1415637-72-7
Chemical Structure
PF-05085727
- CAS No.: 1415637-72-7
- Formula:C20H18F3N7
- Molecular Weight:413.40
IUPAC Name: 4-(azetidin-1-yl)-1-methyl-3-(1-methyl-5-(4-(trifluoromethyl)phenyl)-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidine
InChIKey: SHAVEYUXRBIMLA-UHFFFAOYSA-N
SMILES: CN1C2=NC=NC(N3CCC3)=C2C(C4=C(C5=CC=C(C(F)(F)F)C=C5)N(C)N=C4)=N1
Biological Activity: PF-05085727 is a potent, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM). PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-05085727 | 99.53% | PF-05085727 is a potent, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM). PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. | ||||||||||||||||||||
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PF-05085727 (Standard) | ≥98% | PF-05085727 (Standard) is the analytical standard of PF-05085727 (HY-102050). This product is intended for research and analytical applications. PF-05085727 is a potent, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM). PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11. | ||||||||||||||||||||
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References
Keywords
