1415792-84-5
Chemical Structure
Sovleplenib
Synonym(s): HMPL-523
- CAS No.: 1415792-84-5
- Formula:C24H30N6O3S
- Molecular Weight:482.60
IUPAC Name: (S)-7-(4-(1-(methylsulfonyl)piperidin-4-yl)phenyl)-N-(morpholin-2-ylmethyl)pyrido[3,4-b]pyrazin-5-amine
InChIKey: NJIAKNWTIVDSDA-FQEVSTJZSA-N
SMILES: CS(N(CC1)CCC1C(C=C2)=CC=C2C3=CC(N=CC=N4)=C4C(NC[C@@H]5CNCCO5)=N3)(=O)=O
Biological Activity: Sovleplenib (HMPL-523) is a highly potent, orally available and selective SYK inhibitor with an IC50 of 25 nM. Anti-tumor activity. Sovleplenib can be used for the research of immune thrombocytopenia (ITP)[1].
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Sovleplenib | 99.94% | Sovleplenib (HMPL-523) is a highly potent, orally available and selective SYK inhibitor with an IC50 of 25 nM. Anti-tumor activity. Sovleplenib can be used for the research of immune thrombocytopenia (ITP). | ||||||||||||||||||||
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Keywords