1492952-76-7
1492952-76-7
Chemical Structure
Asciminib
Synonym(s): ABL001
- CAS No.: 1492952-76-7
- Formula:C20H18ClF2N5O3
- Molecular Weight:449.84
IUPAC Name: (R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)nicotinamide
InChIKey: VOVZXURTCKPRDQ-CQSZACIVSA-N
SMILES: O=C(C1=CC(C2=NNC=C2)=C(N3C[C@H](O)CC3)N=C1)NC4=CC=C(OC(F)(Cl)F)C=C4
Biological Activity: Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM[1].
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Asciminib | 99.61% | Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM. | ||||||||||||||||||||
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Asciminib (Standard) | 99.63% | Asciminib (Standard) is the analytical standard of Asciminib. This product is intended for research and analytical applications. Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM. | ||||||||||||||||||||
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References
Keywords
