1619983-52-6

AQX-435 Chemical Structure
1619983-52-6

Chemical Structure

AQX-435

  • CAS No.: 1619983-52-6
  • Formula:C27H34N2O4
  • Molecular Weight:450.57

IUPAC Name: N-((2R,3S,4S,4aS,8aS)-4-(3,5-dihydroxybenzoyl)-3,4a,8,8-tetramethyldecahydronaphthalen-2-yl)nicotinamide

InChIKey: JBBCDNNDYGLMOE-LZITZJIASA-N

SMILES: O=C(C1=CC=CN=C1)N[C@@H]2C[C@@]3([H])C(C)(C)CCC[C@]3(C)[C@@H](C(C4=CC(O)=CC(O)=C4)=O)[C@@H]2C

Biological Activity: AQX-435 is a potent SHIP1 phosphatase activator. AQX-435 reduces PI3K activation downstream of the B-cell receptor (BCR) and induces apoptosis of malignant B cells, and reduces lymphoma growth[1][2].

Cat. No. Product Name Purity Description Pricing
HY-136268 		AQX-435 99.15% AQX-435 is a potent SHIP1 phosphatase activator. AQX-435 reduces PI3K activation downstream of the B-cell receptor (BCR) and induces apoptosis of malignant B cells, and reduces lymphoma growth.
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