166174-54-5
Chemical Structure
L-751788
- CAS No.: 166174-54-5
- Formula:C26H36ClNO2
- Molecular Weight:430.02
IUPAC Name: (4aR,4bS,6aR,8S,9aS,9bS,10S,11aR)-8-(4-chlorophenoxy)-1,4a,6a,10-tetramethylhexadecahydro-2H-indeno[5,4-f]quinolin-2-one
InChIKey: UTVZMYJIIKQMGU-DHWOETJDSA-N
SMILES: O=C1N([C@@]2(C[C@@H]([C@@]3([H])[C@@]4(C[C@@H](C[C@]4(CC[C@@]3([C@]2(CC1)C)[H])C)OC5=CC=C(C=C5)Cl)[H])C)[H])C
Biological Activity: L-751788 is a selective inhibitor of type I of 5α-reductase. L-751788 does not have a significant impact on the differentiation of the external genitalia in animals. When administered orally to pregnant rhesus monkeys, L-751788 (2, 10 mg/kg) did not cause abnormalities in fetal external genitalia[1].
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L-751788 | L-751788 is a selective inhibitor of type I of 5α-reductase. L-751788 does not have a significant impact on the differentiation of the external genitalia in animals. When administered orally to pregnant rhesus monkeys, L-751788 (2, 10 mg/kg) did not cause abnormalities in fetal external genitalia. | |||||||||||||||||||||
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