1798334-07-2
1798334-07-2
Chemical Structure
PF-04822163
- CAS No.: 1798334-07-2
- Formula:C19H17ClN2O2
- Molecular Weight:340.80
IUPAC Name: (S)-4-(6-chloro-2,3-dihydro-1H-inden-1-yl)-7,8-dimethoxyquinazoline
InChIKey: MMLGZRFGZAYZTE-ZDUSSCGKSA-N
SMILES: COC1=C(OC)C=CC2=C([C@H]3CCC4=C3C=C(Cl)C=C4)N=CN=C12
Biological Activity: PF-04822163 is an orally active, selective, and blood-brain barrier permeable PDE1 inhibitor with IC50 values of 2 nM, 2.4 nM, and 7 nM for PDE1A, PDE1B, and PDE1C respectively. PF-04822163 can be used in the research of attention deficit hyperactivity disorder or Parkinson's disease[1].
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PF-04822163 | PF-04822163 is an orally active, selective, and blood-brain barrier permeable PDE1 inhibitor with IC50 values of 2 nM, 2.4 nM, and 7 nM for PDE1A, PDE1B, and PDE1C respectively. PF-04822163 can be used in the research of attention deficit hyperactivity disorder or Parkinson's disease. | |||||||||||||||||||||
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