2095569-76-7
2095569-76-7
Chemical Structure
Enasidenib-d6
Synonym(s): AG-221-d6
- CAS No.: 2095569-76-7
- Formula:C19H11D6F6N7O
- Molecular Weight:479.41
InChIKey: DYLUUSLLRIQKOE-WFGJKAKNSA-N
SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])(O)CNC1=NC(NC2=CC=NC(C(F)(F)F)=C2)=NC(C3=CC=CC(C(F)(F)F)=N3)=N1
Biological Activity: Enasidenib-d6 (AG-221-d6) is the deuterium labeled Enasidenib (HY-18690)[1]. Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively[2].
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Enasidenib-d6 | Enasidenib-d6 (AG-221-d6) is the deuterium labeled Enasidenib (HY-18690). Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively. | |||||||||||||||||||||
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Enasidenib (Standard) | ≥98% | Enasidenib (Standard) is the analytical standard of Enasidenib. This product is intended for research and analytical applications. Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively. | ||||||||||||||||||||
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Enasidenib | 99.93% | Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively. | ||||||||||||||||||||
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References
