2133455-40-8
2133455-40-8
Chemical Structure
SR-14968
- CAS No.: 2133455-40-8
- Formula:C20H20BrCl2N3O
- Molecular Weight:469.20
InChIKey: DJSSLECNUQMYKG-UHFFFAOYSA-N
SMILES: BrC(C=C1)=CC=C1C(C)N2CCC(N(C3=CC(Cl)=C(C=C3N4)Cl)C4=O)CC2
Biological Activity: SR-14968 is a full, allosteric and non-competitive MOR agonist, with an EC50 of 88 nM for MOR in mouse brainstem. SR-14968 stabilizes MOR in a G protein signaling state that is resistant to washout but reversible by antagonists. SR-14968 induces respiratory depression in mice. SR-14968 can be used in pain-related research[1].
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SR-14968 | SR-14968 is a full, allosteric and non-competitive MOR agonist, with an EC50 of 88 nM for MOR in mouse brainstem. SR-14968 stabilizes MOR in a G protein signaling state that is resistant to washout but reversible by antagonists. SR-14968 induces respiratory depression in mice. SR-14968 can be used in pain-related research. | |||||||||||||||||||||
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References
Keywords
