2468639-68-9
Chemical Structure
Protionamide-d7
- CAS No.: 2468639-68-9
- Formula:C9H5D7N2S
- Molecular Weight:187.31
IUPAC Name: 2-(propyl-d7)pyridine-4-carbothioamide
InChIKey: VRDIULHPQTYCLN-NCKGIQLSSA-N
SMILES: S=C(C1=CC(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])=NC=C1)N
Biological Activity: Protionamide-d7 is deuterium labeled Prothionamide. Protionamide (prothionamide) acts on tuberculosis and leprosy[1].
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Protionamide-d7 | Protionamide-d7 is deuterium labeled Prothionamide. Protionamide (prothionamide) acts on tuberculosis and leprosy. | |||||||||||||||||||||
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Prothionamide (Standard) | ≥98% | Prothionamide (Standard) is the analytical standard of Prothionamide (HY-B0306). This product is intended for research and analytical applications. Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy. | ||||||||||||||||||||
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Prothionamide-d5 | Prothionamide-d5 is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy. | |||||||||||||||||||||
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Prothionamide | 99.87% | Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy. | ||||||||||||||||||||
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